ArticleFrontiers in cellular and infection microbiology2024
Vaginal microbiome distinction in women with HPV+, cervical intraepithelial neoplasia, and cervical cancer, a retrospective study.
Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- The Vaginal Microbiota of Adult Malagasy Women of Reproductive Age in the Marovoay District: First Characterization and Exploration of Associations With Human Papillomavirus and Schistosoma haematobium Infections.The Journal of infectious diseases · 2026Article
- Vaginal Microbiota Composition and HPV Genotype-Specific CIN2+ Risk: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2026Article
- Cell cycle gene expression and microbial profiles associated with HPV related cervical neoplasia and cervical microbiome shifts.Scientific reports · 2026Article
- Association between vaginal microecological dysfunction and cervical lesion severity in postmenopausal women: a retrospective study.Frontiers in medicine · 2026Article
- Targeting vaginal dysbiosis: prospects for the application of live biotherapeutics products.Frontiers in microbiology · 2026Review
- Integrating microbiome insights into cervical cancer.Frontiers in medicine · 2026Review
- From dysbiosis to mechanisms: Why cervicovaginal microbiome-HPV studies must catch up with biology.PLoS pathogens · 2025Article
- Article
- Human Papillomavirus and Other Relevant Issues in Cervical Cancer Pathogenesis.International journal of molecular sciences · 2025Review
- The Vaginal Microbiota, Human Papillomavirus, and Cervical Dysplasia-A Review.Medicina (Kaunas, Lithuania) · 2025Review
- Vaginal Microecology Disturbance and Immune Dysregulation Are Associated with Human Papillomavirus Infection: Insights from a Two-year Study of Vaginal Microecology.International journal of general medicine · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Introduction: The vaginal microbiota is a complex and dynamic micro-ecosystem that plays a pivotal role in protecting the host from various pathogens. Previous studies have investigated the diversity of the vaginal microbiome and its association with health outcomes, particularly the development of HPV-related disorders. This study aimed to investigate the correlation between the vaginal microbiota, HPV infection, cervical intraepithelial neoplasias (CINs), and cervical cancers in 69 women. Methods: DNA was extracted from vaginal samples, followed by HPV genotyping through PCR and sequenced of the16S rRNA gene. Results: Our results revealed that Conclusion: These findings suggest that HPV infection and its associated pathological conditions are closely linked to alterations in the vaginal microbiome. This underscores the need for further research to unravel the intricate relationship between HPV genotype infections and vaginal microbiota, which could pave the way for new diagnostic and therapeutic approaches.
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Registered trials
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