Evidence map›Paper›PMID 39897475›Full record

Observational studyClinical interventions in aging2025

Association Between Metabolic Syndrome and Cardiac Autonomic Nervous Function and Cardiorespiratory Fitness in Older Adults: A Retrospective Observational Study with Propensity Score Overlap Weighting.

Ni Cui, Qiuxia Li, Jing Cheng, Tianhua Xing, Peiyao Shi, Yingmei Wang, Min Luo, Yaoshan Dun, Suixin Liu

Abstract readObservational Study
In one paragraph

Observational study in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ni Cui *Division of Cardiac Rehabilitation, Department of Physical Medicine & Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, People's Republic of China.
Qiuxia Li *Division of Cardiac Rehabilitation, Department of Physical Medicine & Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, People's Republic of China.ORCID 0000-0002-0168-5377
Jing Cheng *Department of Cardiovascular medicine, Shenzhen District Yantian People's Hospital, Shenzhen, Guangdong, 518081, People's Republic of China.
Tianhua XingDivision of Cardiac Rehabilitation, Department of Physical Medicine & Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, People's Republic of China.
Peiyao ShiDepartment of Experimental Diagnosis, Shenzhen District Yantian People's Hospital, Shenzhen, Guangdong, 518081, People's Republic of China.
Yingmei WangDepartment of Cardiovascular medicine, Shenzhen District Yantian People's Hospital, Shenzhen, Guangdong, 518081, People's Republic of China.
Min LuoDepartment of Cardiovascular medicine, Shenzhen District Yantian People's Hospital, Shenzhen, Guangdong, 518081, People's Republic of China.
Yaoshan DunDivision of Cardiac Rehabilitation, Department of Physical Medicine & Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, People's Republic of China.ORCID 0000-0001-8642-9024
Suixin LiuDivision of Cardiac Rehabilitation, Department of Physical Medicine & Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Delayed heart rate recovery (HRR) after exercise, an indicator of cardiac autonomic nervous function (CANF), has been found to be associated with metabolic syndrome (MetS) in general populations. However, this relationship has not been extensively studied in older adults. The present study aimed to investigate the association between MetS and HRRs at 1, 2, 3 and 6 minutes after exercise and cardiorespiratory fitness (CRF) in Chinese dwelling older adults. Methods: This retrospective, observational study consecutively enrolled participants aged 60 years or older who underwent physical examinations in Shenzhen District Yantian People's Hospital from September 2019 to July 2021. The participants were categorized into MetS and non-MetS groups according to the International Diabetes Federation criteria. Logistic regression analysis was applied to assess the association between MetS and CANF and CRF. Propensity score overlap weighting was used to adjust the covariates. Results: A total of 987 eligible participants were included (mean age±SD, 66±4 years; male, 47.1%), of whom, 506 were diagnosed with MetS. MetS group showed significantly lower peak heart rate, HRR1-3, HRR6, peak metabolic equivalents, and peak oxygen consumption compared to the non-MetS group. Furthermore, peak systolic and diastolic blood pressures in the MetS group were significantly higher. Logistic regression analysis showed that MetS was significantly associated with HRR2, HRR3 (odds ratio [95% CI], 0.997 [0.995,0.999], both; Conclusion: Elderly Chinese with MetS tend to exhibit reduced CANF and lower CRF. It is recommended that they boost physical activity and closely monitor heart rate and blood pressure during exercise to mitigate exercise-related risks.

Indexed as

Autonomic Nervous SystemCardiorespiratory FitnessHeart RateMetabolic SyndromeAgedBlood PressureChinaExerciseFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective Studiesaging population healthautonomic regulationfitness evaluationgeriatric cardiologyheart rate recoverysystolic blood pressure recovery

Identifiers

PMID39897475
PMCPMC11787786

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.