Evidence map›Paper›PMID 39897241›Full record

ArticleCureus2025

Complete Remission of Plasmablastic Lymphoma With Daratumumab and a Mild Regimen of Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone (Mini-CHOP).

Samuel Z Davis, Wei Cui, Jordan Snyder, Forat Lutfi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel Z DavisSchool of Medicine, University of Kansas Medical Center, Kansas City, USA.
Wei CuiPathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, USA.
Jordan SnyderPharmacology, The University of Kansas Cancer Center, Kansas City, USA.
Forat LutfiHematology, The University of Kansas Cancer Center, Kansas City, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmablastic lymphoma (PBL) is a rare and highly aggressive subtype of diffuse large B-cell lymphoma, characterized by a dismal prognosis. Due to its rarity and aggressive nature, no established standard of care exists for PBL. Treatment is primarily based on large B-cell lymphoma- or multiple myeloma-based chemotherapy regimens, and outcomes remain poor. We present an 84-year-old man with an extensive oncologic history who presented with PBL on his right foot which did not respond to subsequent radiation treatment. A mild regimen of cyclophosphamide, doxorubicin, vincristine, and prednisolone (mini-CHOP) normally utilized to treat large B-cell lymphoma was supplemented with the CD38-directed monoclonal antibody, daratumumab. This combination regimen was selected for the elderly patient due to his weakened condition. Upon six cycles of daratumumab-mini-CHOP, the patient achieved complete remission.

Indexed as

chemotherapy responsechop regimencomplete stable remissiondaratumumabelderly patientsplasmablastic large b-cell lymphoma

Identifiers

PMID39897241
PMCPMC11785514

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.