ArticleCureus2025
A Rare Case of Intravascular Large B-cell Lymphoma Presenting as Fever of Unknown Origin With Unexplained Proteinuria.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- CT-Imaging Manifestations and Diagnostic Insights in Pulmonary Intravascular Large B-Cell Lymphoma: A Case Series and Literature Review.Cancer reports (Hoboken, N.J.) · 2025Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intravascular large B-cell lymphoma (IVLBCL) is a subtype of extranodal diffuse large B-cell lymphoma, characterized by neoplastic B-cell proliferation within blood vessels. Its nonspecific presentation, often as fever of unknown origin (FUO) and systemic symptoms, makes diagnosis challenging. We report the case of a 66-year-old male patient presenting with persistent fever, weight loss, and respiratory failure. Initial investigations, including bone marrow biopsy and imaging, were inconclusive. The lack of response to empirical therapy and the patient's worsening condition presented us with a diagnostic dilemma. The unexplained proteinuria led us to perform a renal biopsy, which confirmed IVLBCL through the identification of atypical B-cells in glomerular capillaries. This case highlights the importance of considering IVLBCL in persistent FUO cases and the role of specific tissue biopsy in diagnosis, even with nonspecific bone marrow studies. Early detection and prompt treatment are crucial, but prognosis remains poor due to diagnostic delays.
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