ArticleFrontiers in public health2024
Rising congenital syphilis rates in Canada, 1993-2022.
Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Rapid/point-of-care syphilis testing in high-income countries: insights and implementation challenges from the authors' experience in Canada.Journal of clinical microbiology · 2026Review
- An exploratory intersectional analysis of lifetime syphilis prevalence among people who inject drugs in Montreal, Canada.Sexually transmitted diseases · 2026Article
- Evaluating the Impact of Implementing and Scaling-Up the Use of Syphilis Rapid/Point-of-Care Tests: An Interrupted Time Series Analysis of New Syphilis Positivity Rates in Alberta, Canada.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- The rise of congenital syphilis in Canada: threats and opportunities.Frontiers in public health · 2024Review
- Development of the W-PREV Model: Integrating HIV/STBBI Prevention and Women's Sexual and Reproductive Healthcare Using an Intersectional Women-Centered Approach.Journal of the International Association of Providers of AIDS CareArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The number of cases of confirmed early congenital syphilis has risen steeply in Canada in recent years, particularly since 2018, to the highest number ever recorded since national reporting began in 1993. We analyzed national data on confirmed early congenital syphilis from 1993 to 2022 to describe epidemiologic trends in Canada during this period. Methods: Data from 1993 to 2017 were obtained from routine surveillance conducted through the Canadian Notifiable Disease Surveillance System, and data from 2018 to 2022 were obtained from enhanced surveillance conducted through a federal-provincial-territorial working group. Case counts and rates were computed nationally and by province and territory. Infectious syphilis data from the same time period for females of reproductive age were also analyzed. Results: The national rate of confirmed early congenital syphilis was 127-fold higher in 2022 than in 1993, increasing from 0.3 to 32.7 cases per 100,000 live births. Case counts began increasing rapidly in 2018, with the highest case count observed to date ( Discussion: These numbers represent huge shifts in the epidemiological landscape of syphilis in Canada. The increase in vertical transmission appears to be driven by not only the increasing rate of infectious syphilis among females of reproductive age but also by multiple structural and social determinants of health impacting pregnant individuals.
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Registered trials
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