ArticleLaryngoscope investigative otolaryngology2025
Three-dimensional cone beam computed tomography analysis of craniofacial phenotype in nonobese apneic young adults.
Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06022679 (CBCT Analysis of the Craniofacial Architecture in Young, Non-overweight Apneic Adult Phenotype), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
CBCT Analysis of the Craniofacial Architecture in Young, Non-overweight Apneic Adult Phenotype
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Role of the Hyoid Bone in Obstructive Sleep Apnea Severity: A Systematic Review.Journal of sleep research · 2026Pooled it
- Multicenter clinical trial for the treatment of obstructive sleep apnea with a non-permanent orthodontic intraoral device in children.European journal of pediatrics · 2025Trial
- Upper airway and hyoid bone-related morphological parameters associated with the apnea-hypopnea index and lowest nocturnal oxygen saturation: a cephalometric analysis.BMC oral health · 2025Article
- Three-dimensional cone beam computed tomography analysis of craniofacial phenotype in nonobese apneic young adults.Laryngoscope investigative otolaryngology · 2025Article
- The Impact of Craniofacial Skeletal Patterns on Sleep Quality and Oral Health-Related Quality of Life Among Adults.Nature and science of sleep · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The obstructive sleep apnea (OSA) syndrome with its various phenotypes, as assessed by the apnea-hypopnea index (AHI), has become a major public health issue. While physicians are regularly faced with a variety of patients with OSA complaints, they may not be aware that OSA in nonobese young adults remains a largely underinvestigated topic. It is hypothesized that, in these subjects, facial bone volumes are smaller than in healthy adults. Methods: This cross-sectional, nonrandomized, controlled study was designed to compare the 3D cephalometric analysis of bone and craniofacial soft tissues in a group of 23 nonobese apneic (AHI ≥ 15), young (18-35 years) adults and in a control group of 23 nonapneic (AHI < 15) healthy subjects by using cone beam computed tomography (CBCT). All subjects were Caucasian and underwent a sleep examination in the Sleep Clinic of the University Hospital of Liege. Results: The two groups were comparable except for age and medications. The maxillary bone volume (23.2 ± 4.6 cm Conclusion: Craniofacial structures that most discerned apneic subjects from controls were the maxillary and mandible bone volumes. An overly narrow maxilla and a postero-rotating mandible were also associated with OSA. Level of Evidence: III. Registration: NCT06022679.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.