ArticleBBA advances2025
Free oligosaccharides in serum.
Article in BBA advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Introduction to a special issue, "Expanded glycomics: A bridge over future glycomics".BBA advances · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glycans are sugars/sugar chains that are usually linked to proteins or lipids. The attachment of glycans often results in alterations of physicochemical/physiological properties of the carrier molecules, e.g., glycosylation of proteins can modulate their fate, intracellular localization, or interaction with cells/other proteins. On the other hand, unconjugated N-glycans (free N-glycans; FNGs) have been identified in the cytosol of eukaryotic cells. The processing pathway of intracellular FNGs has been clarified in recent years, but their biological functions remain unclear. Free oligosaccharides have also been identified in the sera of various animals. Structurally, these extracellular free glycans can be classified into three types: sialyl FNGs, oligomannose-type FNGs, and sialyl lactose/N-acetyllactosamine-type glycans. The extracellular FNGs show different structural features from intracellular FNGs, implying that their mechanism of formation is distinct. This mini-review summarizes current knowledge about the structures and formation mechanisms of free oligosaccharides in serum, and suggests their possible biological functions.
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