Evidence map›Paper›PMID 39896595›Full record

ArticlebioRxiv : the preprint server for biology2025

Co-Conservation of Synaptic Gene Expression and Circuitry in Collicular Neurons.

Yuanming Liu, John A McDaniel, Chen Chen, Lu Yang, Arda Kipcak, Elise L Savier, Alev Erisir, Jianhua Cang, John N Campbell

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Yuanming LiuDepartment of Biology, Charlottesville, VA 22904, USA.
John A McDanielDepartment of Psychology University of Virginia, Charlottesville, VA 22904, USA.
Chen ChenDepartment of Psychology University of Virginia, Charlottesville, VA 22904, USA.
Lu YangDepartment of Biology, Charlottesville, VA 22904, USA.
Arda KipcakDepartment of Psychology University of Virginia, Charlottesville, VA 22904, USA.
Elise L SavierDepartment of Biology, Charlottesville, VA 22904, USA.
Alev ErisirDepartment of Psychology University of Virginia, Charlottesville, VA 22904, USA.
Jianhua CangDepartment of Biology, Charlottesville, VA 22904, USA.
John N CampbellDepartment of Biology, Charlottesville, VA 22904, USA.ORCID 0000-0002-3943-8312

Funding

Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Thomas P. Loughran · 1987 to 2026
$72.1M
Neural Mechanisms of Stereoscopic VisionR01EY020950 · NEI · UNIVERSITY OF VIRGINIA · PI Jianhua Cang · 2010 to 2026
$5.9M
Visual Signal Transformation in the Retinocollicular PathwayR01EY026286 · NEI · UNIVERSITY OF VIRGINIA · PI Jianhua Cang · 2016 to 2026
$4.4M
Molecular and Functional Taxonomy of Cardiovagal NeuronsR01HL153916 · NHLBI · UNIVERSITY OF VIRGINIA · PI CAMPBELL, JOHN NELSON · 2021 to 2025
$3.1M
NCI NIH HHS P30 CA044579NEI NIH HHS R01 EY020950NEI NIH HHS R01 EY026286NHLBI NIH HHS R01 HL153916
6 · The paper itself

Abstract

The superior colliculus (SC), a midbrain sensorimotor hub, is anatomically and functionally similar across vertebrates, but how its cell types have evolved is unclear. Using single-nucleus transcriptomics, we compared the SC's molecular and cellular organization in mice, tree shrews, and humans. Despite over 96 million years of evolutionary divergence, we identified ~30 consensus neuronal subtypes, including

Identifiers

PMID39896595
PMCPMC11785205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.