Evidence map›Paper›PMID 39896552›Full record

ArticlebioRxiv : the preprint server for biology2025

Integrative Mapping of Pre-existing Immune Landscapes for Vaccine Response Prediction.

Stephanie Hao, Ivan Tomic, Benjamin B Lindsey, Ya Jankey Jagne, Katja Hoschler, Adam Meijer, Juan Manuel Carreño Quiroz, Philip Meade, Kaori Sano, Chikondi Peno and 7 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Stephanie HaoAtomic lab, The National Emerging Infectious Diseases Laboratories (NEIDL), Boston University; Boston, MA, US.
Ivan TomicAtomic lab, The National Emerging Infectious Diseases Laboratories (NEIDL), Boston University; Boston, MA, US.ORCID 0000-0003-3596-681X
Benjamin B LindseyThe Florey Institute of Infection and NIHR Sheffield Biomedical Research Centre, University of Sheffield; Sheffield, UK.ORCID 0000-0003-4227-2592
Ya Jankey JagneVaccines and Immunity Theme, Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine; Fajara, The Gambia.
Katja HoschlerRespiratory Virus Unit, UK Health Security Agency; London, UK.
Adam MeijerNational Institute for Public Health and the Environment; Bilthoven, The Netherlands.
Juan Manuel Carreño QuirozDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, US.
Philip MeadeDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, US.
Kaori SanoDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, US.
Chikondi PenoCentre for Inflammation Research, University of Edinburgh; Edinburgh, UK.
André G Costa-MartinsDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo; São Paulo, Brazil.
Debby BogaertCentre for Inflammation Research, University of Edinburgh; Edinburgh, UK.
Beate KampmannVaccines and Immunity Theme, London School of Hygiene & Tropical Medicine; London, UK.
Helder NakayaDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo; São Paulo, Brazil.ORCID 0000-0001-5297-9108
Florian KrammerDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, US.
Thushan I de SilvaThe Florey Institute of Infection and NIHR Sheffield Biomedical Research Centre, University of Sheffield; Sheffield, UK.ORCID 0000-0002-6498-9212
Adriana TomicAtomic lab, The National Emerging Infectious Diseases Laboratories (NEIDL), Boston University; Boston, MA, US.ORCID 0000-0001-9885-3535

Funding

Determining the induction of hemagglutinin stalk and neuraminidase antibody responses after LAIV vaccination in childrenR21AI151917 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2020 to 2021
$466k
Gates Foundation INV-004222NIAID NIH HHS R21 AI151917Wellcome Trust
6 · The paper itself

Abstract

Predicting individual vaccine responses remains a significant challenge due to the complexity and variability of immune processes. To address this gap, we developed

Identifiers

PMID39896552
PMCPMC11785181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.