Evidence map›Paper›PMID 39896458›Full record

ArticlebioRxiv : the preprint server for biology2024

Loss of factor VIII in zebrafish rebalances antithrombin deficiency but has a limited bleeding diathesis.

Catherine E Richter, Azhwar Raghunath, Megan S Griffin, Murat Yaman, Valder R Arruda, Benjamin J Samelson-Jones, Jordan A Shavit

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Catherine E RichterDepartment of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, USA.
Azhwar RaghunathDepartment of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, USA.ORCID 0000-0001-5217-0341
Megan S GriffinDepartment of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, USA.
Murat YamanDepartment of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, USA.
Valder R ArrudaDivision of Hematology and Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Benjamin J Samelson-JonesDivision of Hematology and Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Jordan A ShavitDepartment of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, USA.ORCID 0000-0002-2874-4904

Funding

Genetic and therapeutic studies of hemostatic and thrombotic disorders using zebrafishR35HL150784 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jordan A. Shavit · 2020 to 2026
$5.4M
Rational Development of Bioengineered Factor IX Variants for Hemophilia B TherapyK08HL140078 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI SAMELSON-JONES, BEN J · 2018 to 2021
$638k
NHLBI NIH HHS K08 HL140078NHLBI NIH HHS R35 HL150784
6 · The paper itself

Abstract

Deficiencies in coagulation factor VIII (FVIII,

Identifiers

PMID39896458
PMCPMC11785011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.