Evidence map›Paper›PMID 39896282›Full record

ArticleMaterials today. Bio2025

Fucoidan alginate and sulfated alginate microbeads induce distinct coagulation, inflammatory and fibrotic responses.

Kalaiyarasi Vasuthas, Joachim Sebastian Kjesbu, Alessandro Brambilla, Maya Levitan, Abba Elizabeth Coron, Davi M Fonseca, Berit L Strand, Geir Slupphaug, Anne Mari A Rokstad

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Marine drugs · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kalaiyarasi VasuthasCentre of Molecular Inflammation Research (CEMIR), NTNU, Norway.
Joachim Sebastian KjesbuDepartment of Biotechnology and Food Science, NTNU, Norway.
Alessandro BrambillaDepartment of Clinical and Molecular Medicine, NTNU, Norway.
Maya LevitanCentre of Molecular Inflammation Research (CEMIR), NTNU, Norway.
Abba Elizabeth CoronDepartment of Biotechnology and Food Science, NTNU, Norway.
Davi M FonsecaDepartment of Clinical and Molecular Medicine, NTNU, Norway.
Berit L StrandDepartment of Biotechnology and Food Science, NTNU, Norway.
Geir SlupphaugDepartment of Clinical and Molecular Medicine, NTNU, Norway.
Anne Mari A RokstadCentre of Molecular Inflammation Research (CEMIR), NTNU, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the host response to fucoidan alginate microbeads in comparison to sulfated alginate microbeads, which are relevant for immune protection in cell therapy. While sulfated alginate microbeads reduce fibrosis and inflammation, fucoidan, a kelp-derived polysaccharide rich in sulfate groups, has not been evaluated in this context. The study assesses surface reactivity to acute-phase proteins and cytokines using

Indexed as

ECM-Degrading proteasesFibrinolysisHydrogelsLC/MS-ProteomicsSulfated polysaccharidesSurface

Identifiers

PMID39896282
PMCPMC11783016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.