Evidence map›Paper›PMID 39896245›Full record

ArticleJACC. Asia2025

Outcomes of Left Atrial Appendage Closure in Hemodialysis Patients With Atrial Fibrillation: The OCEAN-LAAC Registry.

Shuhei Tanaka, Teruhiko Imamura, Nobuyuki Fukuda, Hiroshi Ueno, Koichiro Kinugawa, Mitsuru Sago, Ryuki Chatani, Daisuke Hachinohe, Toru Naganuma, Yohei Ohno and 14 more

Abstract read
In one paragraph

Article in JACC. Asia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Left Atrial Appendage Closure: Past, Present, and Future.The Journal of innovations in cardiac rhythm management · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Shuhei TanakaSecond Department of Internal Medicine, University of Toyama, Toyama, Japan.
Teruhiko ImamuraSecond Department of Internal Medicine, University of Toyama, Toyama, Japan.
Nobuyuki FukudaSecond Department of Internal Medicine, University of Toyama, Toyama, Japan.
Hiroshi UenoSecond Department of Internal Medicine, University of Toyama, Toyama, Japan.
Koichiro KinugawaSecond Department of Internal Medicine, University of Toyama, Toyama, Japan.
Mitsuru SagoDepartment of Cardiology, Toyohashi Heart Center, Aichi, Japan.
Ryuki ChataniDepartment of Cardiology, Kurashiki Central Hospital, Okayama, Japan.
Daisuke HachinoheDivision of Cardiovascular Medicine, Sapporo Heart Center, Sapporo Cardio Vascular Clinic, Sapporo, Japan.
Toru NaganumaDepartment of Cardiology, New Tokyo Hospital, Chiba, Japan.
Yohei OhnoDepartment of Cardiology, Tokai University School of Medicine, Kanagawa, Japan.
Tomoyuki TaniDepartment of Cardiology, Sapporo East Tokushukai Hospital, Hokkaido, Japan.
Hideharu OkamatsuDepartment of Cardiology, Saiseikai Kumamoto Hospital, Kumamoto, Japan.
Kazuki MizutaniDepartment of Cardiology, Kinki University school of Medicine, Osaka, Japan.
Yusuke WatanabeDepartment of Cardiology, Teikyo University School of Medicine, Tokyo, Japan.
Masaki IzumoDepartment of Cardiology, St. Marianna University School of Medicine, Kanagawa, Japan.
Mike SajiDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Shingo MizunoDepartment of Cardiology, Shonan Kamakura General Hospital, Kanagawa, Japan.
Shunsuke KuboDepartment of Cardiology, Kurashiki Central Hospital, Okayama, Japan.
Shinichi ShiraiDepartment of Cardiology, Kokura Memorial Hospital, Fukuoka, Japan.
Masaki NakashimaDepartment of Cardiology, Sendai Kousei Hospital, Miyagi, Japan.
Masahiko AsamiDivision of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan.
Masanori YamamotoDepartment of Cardiology, Toyohashi Heart Center, Aichi, Japan.
Kentaro HayashidaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
OCEAN-LAAC Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Left atrial appendage closure (LAAC) has demonstrated favorable outcomes as an alternative to permanent anticoagulation in patients with nonvalvular atrial fibrillation (NVAF). In hemodialysis (HD) patients with NVAF, anticoagulation increases bleeding complications, with inconsistent benefits in stroke prevention. Objectives: This study aimed to clarify the benefit of LAAC for HD patients. Methods: Consecutive patients who underwent LAAC, as extracted from the Japanese multicenter registry, were eligible. When comparing HD and non-HD patients, perioperative events, including LAAC procedure success rates and the incidence of death, bleeding events, and ischemic stroke events, were analyzed. Results: Among 1,464 patients (mean age 77.1 ± 7.6 years, mean CHA Conclusions: LAAC is feasible for HD patients and achieves results comparable to those in non-HD patients. Further research is necessary to determine the effectiveness of LAAC in preventing stroke in HD patients.

Indexed as

anticoagulationhemodialysisischemic strokeleft atrial appendage closurenonvalvular atrial fibrillation

Identifiers

PMID39896245
PMCPMC11782099

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.