Evidence map›Paper›PMID 39896191›Full record

ArticleFrontiers in oncology2024

Evaluating ChatGPT-4o as a decision support tool in multidisciplinary sarcoma tumor boards: heterogeneous performance across various specialties.

Tekoshin Ammo, Vincent G J Guillaume, Ulf Krister Hofmann, Norma M Ulmer, Nina Buenting, Florian Laenger, Justus P Beier, Tim Leypold

Abstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. ChatGPT-4o as a decision-support tool in a urological tumour board: a prospective evaluation.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tekoshin AmmoDepartment of Plastic Surgery, Hand and Reconstructive Surgery, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Vincent G J GuillaumeDepartment of Plastic Surgery, Hand and Reconstructive Surgery, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Ulf Krister HofmannDepartment of Orthopedics, Trauma and Reconstructive Surgery, Division of Arthroplasty, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Norma M UlmerDepartment of Radiation Oncology, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Nina BuentingDepartment of Diagnostic and Interventional Radiology, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Florian LaengerInstitute of Pathology, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Justus P BeierDepartment of Plastic Surgery, Hand and Reconstructive Surgery, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Tim LeypoldDepartment of Plastic Surgery, Hand and Reconstructive Surgery, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: Since the launch of ChatGPT in 2023, large language models have attracted substantial interest to be deployed in the health care sector. This study evaluates the performance of ChatGPT-4o as a support tool for decision-making in multidisciplinary sarcoma tumor boards. Methods: We created five sarcoma patient cases mimicking real-world scenarios and prompted ChatGPT-4o to issue tumor board decisions. These recommendations were independently assessed by a multidisciplinary panel, consisting of an orthopedic surgeon, plastic surgeon, radiation oncologist, radiologist, and pathologist. Assessments were graded on a Likert scale from 1 (completely disagree) to 5 (completely agree) across five categories: understanding, therapy/diagnostic recommendation, aftercare recommendation, summarization, and support tool effectiveness. Results: The mean score for ChatGPT-4o performance was 3.76, indicating moderate effectiveness. Surgical specialties received the highest score, with a mean score of 4.48, while diagnostic specialties (radiology/pathology) performed considerably better than the radiation oncology specialty, which performed poorly. Conclusions: This study provides initial insights into the use of prompt-engineered large language models as decision support tools in sarcoma tumor boards. ChatGPT-4o recommendations regarding surgical specialties performed best while ChatGPT-4o struggled to give valuable advice in the other tested specialties. Clinicians should understand both the advantages and limitations of this technology for effective integration into clinical practice.

Indexed as

artificial intelligencecancerchat-GPTlarge language modelsLLMmultidisciplinary sarcoma tumor boardsarcoma

Identifiers

PMID39896191
PMCPMC11782276

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.