ArticleFrontiers in oral health2025
Decoding gene expression dynamics in planktonic and biofilm cells of
Article in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Dental caries is the most prevalent chronic infectious disease globally, with Methods: Transcriptomic analysis was conducted to examine gene expression patterns in Results: Several genes and operons were differentially expressed across the tested growth phases, with 1,095 genes showing differential expression between stationary-phase, planktonic and biofilm cells. Pathway analysis revealed significant changes in ascorbate metabolism, carbohydrate utilization and transport systems, lipoic acid metabolism, bacterial toxin pathways, two-component regulatory systems, and secondary metabolite biosynthesis. Notably, expression of the Conclusion: This study provides key insights into gene expression dynamics that drive biofilm formation in
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