Evidence map›Paper›PMID 39895997›Full record

ArticleEuropean journal of obstetrics & gynecology and reproductive biology: X2025

Association between Apolipoprotein L1 genetic variants and risk of preeclampsia and preterm birth among U.S. Black women.

Shanshan Sheehy, David Friedman, Chunyu Liu, Kathryn L Lunetta, Gary Zirpoli, Julie R Palmer

Abstract read
In one paragraph

Article in European journal of obstetrics & gynecology and reproductive biology: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Blood pressure andClinical kidney journal · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shanshan SheehySlone Epidemiology Center, Boston University, USA.
David FriedmanBeth Israel Deaconess Medical Center, USA.
Chunyu LiuDepartment of Biostatistics, Boston University School of Public Health, USA.
Kathryn L LunettaDepartment of Biostatistics, Boston University School of Public Health, USA.
Gary ZirpoliSlone Epidemiology Center, Boston University, USA.
Julie R PalmerSlone Epidemiology Center, Boston University, USA.

Funding

A Follow-up Study for Causes of Cancer in Black WomenU01CA164974 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Kimberly A. Bertrand, Yvette C Cozier · 2017 to 2026
$24.0M
Gene Polymorphisms in Relation to Cancer in Black WomenR01CA098663 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI PALMER, JULIE R · 2003 to 2012
$5.3M
Pregnancy complications in relation to stroke risk in African American womenR01MD015085 · NIMHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SHEEHY, SHANSHAN · 2020 to 2022
$1.1M
Apolipoprotein L1 variants and risk of preeclampsia and preterm birth in African American womenR21HD105201 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SHEEHY, SHANSHAN · 2021 to 2022
$470k
NCI NIH HHS R01 CA098663NCI NIH HHS U01 CA164974NICHD NIH HHS R21 HD105201NIMHD NIH HHS R01 MD015085
6 · The paper itself

Abstract

Background: Preeclampsia and preterm birth disproportionally affects Black women, but the current understanding of genetic predisposition to preeclampsia and preterm birth is rudimentary. It has been hypothesized that carriers of high-risk genetic variants in the apolipoprotein L1 gene ( Objective: To examine whether Study design: We conducted a retrospective case-control study of 6616 Black women from the Black Women's Health Study, a cohort of self-identified Black women in the U.S. Genotype data on Results: The odds ratio (OR) of preeclampsia for two Conclusions: This large prospective study from a general population of Black women found no evidence of an association of

Indexed as

Apolipoprotein L1Black AmericanPreeclampsiaPreterm birth

Identifiers

PMID39895997
PMCPMC11783058

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.