Evidence map›Paper›PMID 39895968›Full record

ArticleeNeurologicalSci2025

Intraoperative neuromonitoring as an independent predictor for postoperative delirium in ICU following aneurysm clipping.

Abdullah M Al-Qudah, Pooja S Tallapaneni, Donald J Crammond, Jeffrey Balzer, Katherine M Anetakis, Varun Shandal, Jingyuan Biaesch, Malik Ghannam, Neelesh Nadkarni, Bradley A Gross and 4 more

Abstract read
In one paragraph

Article in eNeurologicalSci, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Abdullah M Al-QudahCenter of Clinical Neurophysiology, Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Pooja S TallapaneniDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Donald J CrammondCenter of Clinical Neurophysiology, Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Jeffrey BalzerCenter of Clinical Neurophysiology, Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Katherine M AnetakisCenter of Clinical Neurophysiology, Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Varun ShandalCenter of Clinical Neurophysiology, Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Jingyuan BiaeschDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Malik GhannamDepartment of Neurology, University of Iowa Hospital and Clinics, Iowa city, IA, United States of America.
Neelesh NadkarniDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Bradley A GrossDepartment of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Michael LangDepartment of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Kathirvel SubramaniumDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Senthilkumar SadhasivamDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Parthasarathy D ThirumalaCenter of Clinical Neurophysiology, Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aims to evaluate the diagnostic accuracy of significant intraoperative neurophysiological monitoring (IONM) changes as an independent predictor of postoperative delirium (POD) in patients undergoing aneurysm clipping. Methods: IONM and clinical data from 273 patients who underwent craniotomy for aneurysm clipping from 2019 until 2021 were retrospectively reviewed. Significant IONM changes and POD were respectively evaluated based on visual review of data and clinical documentation. POD was assessed multiple times in the ICU using the Intensive Care Delirium Screening Checklist (ICDSC). Results: Of the 273 patients undergoing craniotomy with IONM, 83 had POD (30.4 %). Significant IONM changes were noted in 42 patients, of which 19 patients had POD (45.2 %). In contrast, 231 patients had no IONM changes during surgery, of which 64 (27.7 %) patients had POD. Multivariable analysis showed that significant IONM changes were associated with POD, OR: 2.09 (95 % CI 1.01-4.43, Conclusion: Significant IONM changes are associated with an increased risk of POD in patients undergoing craniotomy for aneurysm clipping. Our findings offer a strong basis for future research and analysis of EEG and SSEP monitoring to detect and possibly prevent POD.

Indexed as

AneurysmClippingCraniotomyDeliriumُEEGICUIntraoperative neurophysiologic monitoringSSEP

Identifiers

PMID39895968
PMCPMC11786857

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.