Evidence map›Paper›PMID 39895857›Full record

ArticleContemporary clinical trials communications2025

The hypotension prediction index in major abdominal surgery - A prospective randomised clinical trial protocol.

Jakub Szrama, Agata Gradys, Zuzanna Nowak, Ashish Lohani, Krzysztof Zwoliński, Tomasz Bartkowiak, Amadeusz Woźniak, Tomasz Koszel, Krzysztof Kusza

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In one paragraph

Article in Contemporary clinical trials communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06247384 (The Hypotension Prediction Index in Major Abdominal Surgery - a Prospective Randomized Clinical Trial.), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06247384 narecruitingnot on this map

The Hypotension Prediction Index in Major Abdominal Surgery - a Prospective Randomized Clinical Trial.

TypeinterventionalSponsorJakub SzramaRan2025 to 2025Enrolled226ConditionsHypotension During SurgeryArmsHypotension Prediction Index Hemodynamic Monitoring
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jakub SzramaDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355, Poznan, Poland.
Agata GradysDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355, Poznan, Poland.
Zuzanna NowakDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355, Poznan, Poland.
Ashish LohaniDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355, Poznan, Poland.
Krzysztof ZwolińskiDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355, Poznan, Poland.
Tomasz BartkowiakDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355, Poznan, Poland.
Amadeusz WoźniakDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355, Poznan, Poland.
Tomasz KoszelDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355, Poznan, Poland.
Krzysztof KuszaDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355, Poznan, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients undergoing major abdominal surgery are at increased risk of developing perioperative hypotension, which is associated with increased mortality and morbidity. Despite using advanced technologies such as evaluating arterial pressure derived cardiac output, anaesthetic management to maintain hemodynamic stability is still reactive when the clinical decision is made after hypotension has developed. Previous perioperative goal-directed studies have not proven the benefits of this approach with high certainty. A new, approved technology called the Hypotension Prediction Index (HPI) aims to prevent hypotension occurrence by allowing the precise hemodynamic monitoring of patients under general anaesthesia, significantly reducing intraoperative hypotension events. This prospective randomised clinical trial aims to compare the rate of perioperative hypotension in patients undergoing major abdominal surgery according to their type of hemodynamic monitoring. Methods: Ethics and dissemination: This trial was approved by the Ethics Committee of the Poznan University of Medical Sciences (KB-559/220; date: 01/07/2022). Its results will be submitted for publication in a peer-reviewed journal. Trial registration number: NCT06247384.

Indexed as

Arterial pressure cardiac outputHypotension prediction indexMajor abdominal surgeryPerioperative hemodynamic management

Identifiers

PMID39895857
PMCPMC11784284

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.