Evidence map›Paper›PMID 39895684›Full record

ArticleJournal of dental research, dental clinics, dental prospects2024

Erosive potential of children's chewable vitamin supplements: An in vitro investigation.

Wannee Lertsooksawat, Yanisa Tanjaruphan, Thanawat Chaima, Thanawat Lerdpibulchai, Tanawan Wittayathawornwong, Chayada Teanchai, Rudee Surarit, Sivaporn Horsophonphong

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Article in Journal of dental research, dental clinics, dental prospects, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wannee LertsooksawatDepartment of Pharmacology, Faculty of Dentistry, Mahidol University, Thailand.ORCID https://orcid.org/0000-0002-0494-8611
Yanisa TanjaruphanUndergraduate Program, Faculty of Dentistry, Mahidol University, Thailand.
Thanawat ChaimaUndergraduate Program, Faculty of Dentistry, Mahidol University, Thailand.
Thanawat LerdpibulchaiUndergraduate Program, Faculty of Dentistry, Mahidol University, Thailand.
Tanawan WittayathawornwongUndergraduate Program, Faculty of Dentistry, Mahidol University, Thailand.
Chayada TeanchaiDepartment of Oral Biology, Faculty of Dentistry, Mahidol University, Thailand.
Rudee SuraritFaculty of Dentistry, Siam University, Thailand.ORCID https://orcid.org/0000-0003-2984-1279
Sivaporn HorsophonphongDepartment of Pediatric Dentistry, Faculty of Dentistry, Mahidol University, Thailand.ORCID https://orcid.org/0000-0002-3315-2989

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chewable vitamins are dietary supplements in which vitamins are combined with a flavor that appeals to children. The acidic nature of some vitamins and some flavoring agents may cause dental erosion. We investigated the effect of children's chewable vitamin supplements on the loss of minerals in teeth. Methods: Forty-two human tooth enamel samples were prepared and randomly assigned to seven groups (n=6). Six groups contained different chewable vitamin tablets dissolved in deionized water, and a control group contained only deionized water. Each tablet was ground before its dissolution, and its pH was measured. Each tooth sample was immersed in a vitamin solution and artificial saliva in periodic cycles for 14 days. Each sample was weighed before and after immersion to calculate its weight loss percentage. Scanning electron microscopy was used to investigate the morphology of the enamel surfaces. For statistical analysis, the weight loss percentages between groups were compared using Welch's ANOVA, followed by post hoc Dunnett's T3 analysis ( Results: All the tested supplements were acidic, with a pH range of 2.99‒4.77. Most of the vitamin groups tested led to significant weight loss; it was greater for the vitamin C groups than the multivitamin groups. Scanning electron microscopy revealed erosion and destruction of enamel surfaces following vitamin exposure. Conclusion: All the chewable vitamin supplements were acidic, with the majority potentially eroding enamel. The erosive potential was less pronounced in vitamin supplements containing minerals.

Indexed as

ChildrenDental erosionDietary supplementsVitamins

Identifiers

PMID39895684
PMCPMC11786007

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.