ArticleAllergy, asthma & immunology research2025
Diagnostic Decision Points of Specific Immunoglobulin E Concentrations for Seafood Allergies in Korean Children: A Nationwide Multicenter Study.
Article in Allergy, asthma & immunology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Addressing Limitations in Oral Food Challenge Testing in Children With Seafood Allergies.Allergy, asthma & immunology research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Shellfish and fish are common causes of food allergy (FA) in Asia, with significant prevalence rates reported across various countries. This study aimed to identify the diagnostic decision points (DDPs) for shrimp, crab, and cod allergies in Korean children. We enrolled participants aged 18 years or younger with suspected shrimp, crab, or cod allergies through a retrospective review of medical records from a nationwide 14-center study between January 2018 and March 2022. FA was diagnosed using an open oral food challenge or a reproducible and convincing history with positive serum specific immunoglobulin E (sIgE) levels. The sIgE cut-off values for shrimp, crab, and cod were determined by analyzing receiver operating characteristic curves. Out of 266 children, 90 (33.8%) were confirmed to have a shrimp allergy. Crab allergies were found in 37 (39.8%) of 93 children. Of 66 children, 15 (22.7%) were found to be allergic to cod. The optimal sIgE cut-off values based on the largest area under the curve were 1.43, 3.25, and 2.05 kU/L for shrimp, crab, and cod, respectively. Levels of sIgE with more than 90% positive predictive value (PPV) were 33.8, 47.5, and 29.9 kU/L for shrimp, crab, and cod, respectively. Levels of sIgE with greater than 90% negative predictive value (NPV) were 0.36, 0.04, and 3.93 kU/L for shrimp, crab, and cod, respectively. Our results suggest that DDPs of sIgE levels with high PPV and NPV can be used to diagnose shrimp, crab, and cod allergies in Korean children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.