ReviewAllergy, asthma & immunology research2025
Skin Barrier Function in Neonates and Infants.
Review in Allergy, asthma & immunology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Topical application of emollients to maintain skin integrity in preterm neonates: a systematic review and meta-analysis.European journal of pediatrics · 2026Pooled it
- Neurodevelopmental Outcomes Associated with Early-Life Exposure to Heavy Metals: A Systematic Review.International journal of environmental research and public health · 2025Pooled it
- Skin Aging and Carotenoids: A Systematic Review of Their Multifaceted Protective Mechanisms.Nutrients · 2025Pooled it
- Negative pressure wound therapy in infants with complex abdominal wounds: A systematic review of clinical applications and closure strategies.JPRAS open · 2026Review
- Population Pharmacokinetics of Topical Timolol Maleate Gel in Healthy Volunteers and Infants With Superficial Infantile Hemangioma.CPT: pharmacometrics & systems pharmacology · 2026Article
- Optimizing Pediatric Drug Therapy: Pediatric Pharmacokinetics and Administration Routes.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Skin Barrier Modulation and Survival-Relevant Outcomes: A Systematic Review of Topical Emollients in Preterm Infants.Cureus · 2026Review
- Immunonutrition: Feeding the gut, skin, and immune system.Asia Pacific allergy · 2026Review
- Article
- RSV infection-associated pediatric generalized pustular psoriasis with innate immune activation: a case report.Frontiers in immunology · 2026Article
- Comparative Effects of Injectable Biostimulatory Agents (Calcium Hydroxyapatite, New Cellular Treatment Factor, VAMP, and Human Exosomes) and Their Combination on Skin Regeneration.Aesthetic surgery journal. Open forum · 2026Article
- Fungal DNA profiles across maternal and neonatal biological sites: findings from an exploratory pilot study.Frontiers in microbiology · 2026Article
- Development and internal validation of machine learning-based models for predicting admission hypothermia in preterm infants: a retrospective cohort study.Frontiers in medicine · 2026Article
- Congenital and Neonatal Skin Disorders: Histopathological Diagnosis and Syndromic Associations.Cureus · 2025Review
- Prevention of Atopic Dermatitis: What Are We Missing?Allergy, asthma & immunology research · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review focuses on the skin barrier function in neonates and infants, emphasizing the structural and functional differences compared to adult skin. Neonatal and infant skin is thinner, more permeable, and less developed, which makes it more vulnerable to irritants, infections, and dehydration. Additionally, the critical role of skin pH in maintaining barrier function is discussed, noting significant changes in pH levels during early life. This review also examines the relationship between the onset of atopic dermatitis and skin barrier function, underscoring the importance of maintaining skin barrier integrity from birth to reduce the risk of atopic diseases. Finally, recommendations are offered for skincare practices in neonates and infants, emphasizing the use of mild, fragrance-free products and the importance of tailoring skincare regimens to meet the specific needs of each neonate or infant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.