ReviewMacromolecular rapid communications2025
Thermo-Responsive Polymer-Based Nanoparticles: From Chemical Design to Advanced Applications.
Review in Macromolecular rapid communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Tumor Microenvironment-Responsive Polymeric Nanocarriers for the Treatment of Triple-Negative Breast Cancer.Pharmaceutics · 2026Review
- A Review of Preparation Methods, Mechanisms, and Applications of Bio-Based Phenolic Nanoparticles.Foods (Basel, Switzerland) · 2026Review
- Peripheral Dendritic Functionalization Effects on the Self-Assembly and Thermoresponsive Behavior of Nonionic Amphiphilic Linear-Dendritic Block Copolymers in Aqueous Media.Macromolecules · 2026Article
- Silver Nanoparticles and Neurotoxicity: Mechanistic Insights and Recent Experimental Evidence.Pharmaceutics · 2026Review
- Self-assembling nanocomposites for smart drug delivery: towards personalized and stimuli-responsive therapeutics.RSC advances · 2026Review
- The Design Strategies and Applications of Engineered Nanoparticles for Traumatic Brain Injury.International journal of nanomedicine · 2026Review
- pH-Thermo Dual-Responsive Polymeric Nanoparticles for Women's Health: Dual Action Against Cervical and Ovarian Cancer Cells.ACS applied materials & interfaces · 2025Article
- Recent Advances of Silver Nanoparticles in Wound Healing: Evaluation of In Vivo and In Vitro Studies.International journal of molecular sciences · 2025Review
- Thermo-Responsive Polymer-Based Nanoparticles: From Chemical Design to Advanced Applications.Macromolecular rapid communications · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thermo-responsive polymers have emerged as a cutting-edge tool in nanomedicine, paving the way for innovative approaches to targeted drug delivery and advanced therapeutic strategies. These "smart" polymers respond to temperature changes, enabling controlled drug release in pathological environments characterized by high temperatures. By exploiting their unique phase transition, occurring at the lower or upper critical solution temperatures (LCST and UCST), these systems ensure localized therapeutic action, minimizing collateral damage to healthy tissues. The integration of these polymers into nanoparticles with hydrophilic shells and hydrophobic cores enhances their stability and biocompatibility. Furthermore, advanced polymer engineering allows precise modulation of LCST and UCST through adjustments in composition and hydrophilic-lipophilic balance, optimizing their responsiveness for specific applications. In addition to drug delivery, thermo-responsive nanoparticles are gaining attention in several fields such as gene therapy and imaging. Therefore, this review explores the chemical and structural diversity of thermo-responsive nanoparticles, emphasizing their ability to encapsulate and release drugs effectively. Second, this review highlights the potential of thermo-responsive nanoparticles to redefine treatment paradigms, providing a comprehensive understanding of their mechanisms, applications, and future perspectives in biomedical research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.