ArticleMedical microbiology and immunology2025
Cytolethal distending toxin-producing Escherichia coli clinical isolates from Mexican children harbor different cdt types causing CDT-induced epithelial pathological phenotypes.
Article in Medical microbiology and immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Cytolethal distending toxin enhancesInfection and immunity · 2026Article
- Cytolethal Distending Toxin EnhancesbioRxiv : the preprint server for biology · 2026Article
- STEC in the natural environment of Uruguay: genomic surveillance and environmental circulation in the framework of One Health.Microbiology spectrum · 2026Article
- TM9SF4 acts as a receptor mediatingFrontiers in cellular and infection microbiology · 2026Article
- New diagnostic methods forFrontiers in microbiology · 2025Article
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Authors and funding
5 authors.
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Abstract
Cytolethal distending toxins (CDTs), encoded by cdtABC genes, have DNase activity leading to cellular and nuclear distention, resulting in actin remodeling, irreversible cell cycle arrest and apoptosis of target cells. PCR cdt-positive Escherichia coli strains have been isolated from children with diarrhea worldwide. However, toxin production and biological activity of cdt
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