Evidence map›Paper›PMID 39894828›Full record

ArticleBMC public health2025

Blood lead levels and bladder cancer among US participants: NHANES 1999-2018.

Mei Huang, Hongxiao Li, Jiahui Chen, Liuqiang Li, Yifei Zhan, Yuxuan Du, Jun Bian, Meiling Chen, Dehui Lai

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Evidence for Genotype-Specific Optimal Blood Lead Levels for Cancer Risk:International journal of molecular sciences · 2026
    Article
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mei Huang *Department of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, Guangdong, 510700, China.
Hongxiao Li *Department of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, Guangdong, 510700, China.
Jiahui ChenDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, Guangdong, 510700, China.
Liuqiang LiDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, Guangdong, 510700, China.
Yifei ZhanDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, Guangdong, 510700, China.
Yuxuan DuDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, Guangdong, 510700, China.
Jun BianDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, Guangdong, 510700, China. bianjun39@163.com.
Meiling ChenDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, Guangdong, 510700, China. 416406696@qq.com.
Dehui LaiDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, Guangdong, 510700, China. dehuilai@hotmail.com.

Funding

Department of Higher Education of the Ministry of Education 220904082210823Guangdong Provincial Natural Science Foundation Committee 2017A030310148Guangdong Provincial Natural Science Foundation Committee 2021A1515010065Guangzhou Medical University 106Guangzhou Municipal Health Commission 20211A011103Guangzhou Municipal Science and Technology Bureau 202201010834
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPb (lead) is a heavy metal, its carcinogenicity for bladder cancer is still debated, the link between blood lead levels (BLLs) and bladder cancer was investigated in this study.

methodsThis cross-sectional study, using the NHANES (1999-2018) database, explored the relationship between BLLs and bladder cancer among Americans aged 20-85. It employed weighted multivariable logistic regression for analysis. Additionally, subgroup analyses and smoothed curve fitting were also performed.

resultsThis study included a total of 40,486 participants, the body mass index (BMI) of the participants is 28.71 ± 6.68 kg/m

conclusionIn this cross-sectional study, we found that the degree of correlation between BLLs and the risk of bladder cancer may vary among people with different BMIs. In people with BMI < 28 kg/m

Indexed as

LeadUrinary Bladder NeoplasmsAdultAgedAged, 80 and overBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysRisk FactorsUnited StatesYoung AdultLeadBladder cancerBlood lead levelCarcinogenicityNational Health and Nutrition Examination Survey (NHANES)

Identifiers

PMID39894828
PMCPMC11787758

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.