Evidence map›Paper›PMID 39894819›Full record

ArticleNPJ digital medicine2025

AI prediction model for endovascular treatment of vertebrobasilar occlusion with atrial fibrillation.

Zhi-Xin Huang, Andrea M Alexandre, Alessandro Pedicelli, Xuying He, Quanlong Hong, Yongkun Li, Ping Chen, Qiankun Cai, Aldobrando Broccolini, Luca Scarcia and 19 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Zhi-Xin HuangNeuroMedical Center, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, 510317, China. hzxd6@163.com.
Andrea M AlexandreUOC Radiologia e Neuroradiologia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, 00168, Italy.
Alessandro PedicelliUOC Radiologia e Neuroradiologia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, 00168, Italy.
Xuying HeNeuroMedical Center, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, 510317, China.
Quanlong HongDepartment of Neurology, Quanzhou First Hospital, Quanzhou, Fujian, 362000, China.
Yongkun LiDepartment of Neurology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, 350000, China.
Ping ChenDepartment of Neurology, The First Hospital of Putian City, Putian, Fujian, 351100, China.
Qiankun CaiDepartment of Neurology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, 362000, China.
Aldobrando BroccoliniNeurology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, 00118, Italy.
Luca ScarciaNeuroradiology Unit, Henri Mondor Hospital, Creteil, 94000, France.
Serena AbruzzeseCatholic University School of Medicine, Rome, 00153, Italy.
Carlo CirelliDepartment of Human Neurosciences, Interventional Neuroradiology, University Hospital Policlinico Umberto I, Rome, 00118, Italy.
Mauro BerguiDepartment of Neuroscience, Neuroradiological Unit, University of Turin, Azienda Ospedaliera Città della Salute e della Scienza Hospital, Torino, 10139, Italy.
Andrea RomiNeuroradiology Unit, IRCCS Policlinico San Matteo, Pavia, 27100, Italy.
Erwah KalsoumNeuroradiology Unit, Henri Mondor Hospital, Creteil, 94000, France.
Giulia FrauenfelderNeuroradiology Unit, AOU S Giovanni di Dio e Ruggi di Aragona, Salerno, 84122, Italy.
Grzegorz MederDepartment of Interventional Radiology, Jan Biziel University Hospital No. 2, Ujejskiego 75 Street, 85-168, Bydgoszcz, Poland.
Simona ScaliseUOC Neurologia-Stroke Unit, Ospedale Vito Fazzi, Lecce, 73100, Italy.
Maria Porzia GanimedeInterventional Radiology Unit, "SS Annunziata" Hospital, Taranto, 74121, Italy.
Luigi BelliniDepartment of Biomedicine and Prevention, University hospital of Rome "Tor Vergata", Rome, 00118, Italy.
Bruno Del SetteNeuroradiology Unit, IRCCS Ospedale Policlinico San Martino, Genova, 16158, Italy.
Francesco ArbaStroke Unit, AOU Careggi University Hospital, Florence, 01062, Italy.
Susanna SammaliNEUROFARBA Department, University of Florence, Florence, 01062, Italy.
Andrea SalcuniDepartment of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome, Rome, 00118, Italy.
Sergio Lucio VinciNeuroradiology Unit, Biomedical Sciences and of Morphologic and Functional Images, AOU Policlinico G. Martino, Messina, 98100, Italy.
Giacomo CesterNeuroradiology Unit, Policlinico Universitario di Padova, Padua, 35100, Italy.
Luisa RoveriNeurology Unit, stroke unit, IRCCS San Raffaele University Hospital, Milan, 20121, Italy.
Xianjun HuangDepartment of Neurology, Yijishan Hospital, Wannan Medical College, Wuhu, 241000, Anhui, China.
Wen SunDepartment of Neurology, Centre for Leading Medicine and Advanced Technologies of IHM, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230000, Anhui, China. sunwen_medneuro@163.com.

Funding

Research Funds of Centre for Leading Medicine and Advanced Technologies of IHM 2023IHM01050Research Funds of Centre for Leading Medicine and Advanced Technologies of IHM 2023IHM01052the Science and Technology Program of Guangzhou, China 2024B03J0436
6 · The paper itself

Abstract

Endovascular treatment (EVT) for vertebrobasilar artery occlusion (VBAO) with atrial fibrillation presents complex clinical challenges. This comprehensive multicenter study of 525 patients across 15 Chinese provinces investigated nuanced predictors beyond conventional metrics. While 45.1% achieved favorable outcomes at 90 days, our advanced machine learning approach unveiled subtle interaction effects among clinical variables not captured by traditional statistical methods. The predictive model distinguished high-risk subgroups by integrating multiple parameters, demonstrating superior prognostic precision compared to standard NIHSS-based assessments. Novel findings include nonlinear relationships between dyslipidemia, stroke severity, and functional recovery. The developed predictive algorithm (AUC 0.719 internally, 0.684 externally) offers a more sophisticated risk stratification tool, potentially guiding personalized treatment strategies in high-complexity VBAO patients with atrial fibrillation.

Identifiers

PMID39894819
PMCPMC11788420

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.