ArticleEuropean heart journal2025
Hospitalization for cardiovascular disease in the year after delivery of twin pregnancies.
Article in European heart journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Single or Double Embryo Transfer for Infertility: An Evaluation of Registry Data From Over 22 000 Treatment Cycles.Deutsches Arzteblatt international · 2026Article
- Placental Abruption, Preterm Delivery, and Cardiovascular Disease in Twin Offspring.Journal of the American Heart Association · 2026Article
- Longitudinal maternal hemodynamics from late pregnancy to postpartum in uncomplicated twin pregnancies-A glimpse into long-term cardiovascular risk?Acta obstetricia et gynecologica Scandinavica · 2026Article
- Twin pregnancies: impact of infertility treatments and postpartum lifestyle on maternal heart health.European heart journal · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
BACKGROUND AND
aimsIncreased cardiovascular demand in twin pregnancies, even those without hypertensive disease of pregnancy (HDP), may pose a greater risk for cardiovascular complications compared with singletons. In this study, the risk of cardiovascular disease (CVD)-related hospitalizations and mortality within the year following delivery in relation to HDP was compared between twin and singleton pregnancies.
methodsUsing the Nationwide Readmissions Database of US hospitals from 2010 to 2020, the rates of CVD readmission in four exposure groups (twin deliveries with and without HDP and singleton deliveries with and without HDP) were estimated. Cox proportional hazard regression models were used to determine associations with singletons without HDP as the reference.
resultsOf 36 million delivery hospitalizations, the rates of CVD readmission in twin and singleton pregnancies were 1105.4 and 734.1 per 100 000 delivery admissions, respectively. Compared with singletons without HDP, the adjusted hazard ratio (HR) of CVD readmission was highest for twins with HDP [HR 8.21, 95% confidence interval (CI) 7.48-9.01], followed by singletons with HDP (HR 5.89, 95% CI 5.70-6.08) and then twins without HDP (HR 1.95, 95% CI 1.75, 2.17).
conclusionsCompared with singletons without HDP, twin pregnancies, even in the absence of HDP, are associated with increased risks for CVD complications in the first year post-partum. These findings highlight the increased strain twin pregnancies place on the maternal cardiovascular system. These findings advocate the need for appropriate pre-conception counselling for those with cardiovascular risk factors undergoing infertility treatment, which increase the risks of multi-foetal gestation, and increased post-partum surveillance in twin pregnancies.
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