SynthesisYonsei medical journal2025
Ultrasound-Guided Nerve Hydrodissection for the Management of Carpal Tunnel Syndrome: A Systematic Review and Network Meta-Analysis.
Synthesis in Yonsei medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07207460 (Comparison of Hydrodissection Techniques Using 5% Dextrose for the Treatment of Carpal Tunnel Syndrome), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Hydrodissection Techniques Using 5% Dextrose for the Treatment of Carpal Tunnel Syndrome
Who cites it
15 citing papers in PubMed.
- Sono-Anatomy and Histology of the Deep Fasciae in the Upper Limb.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Review
- Recent Advances in Ultrasound-Guided Hydrodissection and Dextrose Prolotherapy for Musculoskeletal Pain: A Target-Based State-of-the-Art Narrative Review.Life (Basel, Switzerland) · 2026Review
- Review
- Ultrasound-Guided Nerve Hydrodissection for Sural Nerve Injury: A Case Report and Review of the Literature.Clinical case reports · 2026Article
- Ultrasound-Guided Lumbar Nerve Root Hydrodissection: Fluoroscopy-Assisted Evaluation of Injectate Distribution and Feasibility.Spine surgery and related research · 2026Article
- Ultrasound-Guided Hydrodissection for Carpal Tunnel Syndrome with Bifid Median Nerve and Persistent Median Artery: An Imaging-Based Case Report with Alpha-2 Macroglobulin.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- Ultrasound-Guided Hydrodissection for Neurogenic Thoracic Outlet Syndrome Caused by a Cervical Rib: A Case Report.Cureus · 2026Article
- Ultrasound-guided hydrodissection combined with acupotomy for moderate-to-severe Carpal tunnel syndrome: electrophysiological and ultrasonographic outcomes and their potential relationship to neuroinflammatory attenuation.Frontiers in cell and developmental biology · 2026Article
- Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration.Iranian journal of basic medical sciences · 2026Review
- Review
- Article
- Ulnar Neuropathy Hydrodissection With Platelet Lysate and Prolotherapy: A Case Series and Review of the Literature.Cureus · 2025Article
- Clinical application of ultrasound-guided acupotomy combined with platelet-rich plasma in the treatment of carpal tunnel syndrome.Frontiers in surgery · 2025Article
- A Novel Therapeutic Approach Targeting Spinal Accessory and Dorsal Scapular Nerves for the Relief of Posterior Neck, Trapezius, and Interscapular Pain.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeUltrasound-guided nerve hydrodissection has emerged as a potential non-surgical treatment for carpal tunnel syndrome (CTS). The objective of this research was to offer suggestions for optimizing injectables utilized in hydrodissection for the treatment of CTS through a systematic review and network meta-analysis. MATERIALS AND
methodsPubMed, MEDLINE, EMBASE, Cochrane, Scopus, and Web of Science were searched through April 25, 2024. Effect sizes were quantified using standard mean differences within a random-effects model. Effectiveness ranking for each treatment was expressed as the surface under the cumulative ranking curve (SUCRA).
resultsNine studies with 458 patients with CTS were included. According to SUCRA, 5% dextrose (DW) was the most effective option for the Boston Carpal Tunnel Questionnaire (BCTQ) function at 99.9, 89.8, and 88.8 at 4, 12, and 24 weeks, respectively; for BCTQ symptoms, 5% DW was the most effective option at 99.9 at 4 weeks and platelet-rich plasma at 95.7 and 93.9 at 12 and 24 weeks, respectively. In terms of both BCTQ symptoms and BCTQ function, the 5 cc injection was the most effective, with SUCRA values of 99.5 for both categories. However, the effectiveness of the electrodiagnostic assessment and ultrasound variables was dependent on the type and dose of medication.
conclusionAdministration of 5% DW showed better results in terms of initial symptom relief and long-term functional recovery compared to other agents, while platelet-rich plasma showed greater long-term symptom improvement; an injection dose of 5 cc showed the greatest benefit. However, additional research is required to establish precise protocols based on disease severity.
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