Evidence map›Paper›PMID 39893463›Full record

ArticleMalaria journal2025

Voices from the Amazon: exploring implementor and user perceptions of non-invasive malaria diagnostics in Peru.

Lauren Nussbaum, Emma Ortega, E Jennifer Ríos López, Alfonso Simoné Vizcarra, Jhonny J Córdova López, Serafina Calarco, Elena Marbán-Castro, Kevin Tetteh, Sonjelle Shilton, Amy C Morrison and 2 more

Abstract read
In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lauren NussbaumDepartment of Tropical Medicine and Infectious Disease, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Emma OrtegaDepartment of Tropical Medicine and Infectious Disease, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
E Jennifer Ríos LópezBehavioral Sciences Research Unit, Asociación Benéfica PRISMA, Iquitos, Peru.
Alfonso Simoné VizcarraBehavioral Sciences Research Unit, Asociación Benéfica PRISMA, Iquitos, Peru.
Jhonny J Córdova LópezBehavioral Sciences Research Unit, Asociación Benéfica PRISMA, Iquitos, Peru.
Serafina CalarcoFIND, Geneva, Switzerland.
Elena Marbán-CastroFIND, Geneva, Switzerland.
Kevin TettehFIND, Geneva, Switzerland.
Sonjelle ShiltonFIND, Geneva, Switzerland.
Amy C Morrison *Behavioral Sciences Research Unit, Asociación Benéfica PRISMA, Iquitos, Peru.
Vanessa Fargnoli *FIND, Geneva, Switzerland.
Valerie A Paz-Soldán *Department of Tropical Medicine and Infectious Disease, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA. vpazsold@tulane.edu.

Funding

Swiss Development Corporation 81071426UK Aid FCDO 300341-102
6 · The paper itself

Abstract

backgroundMalaria burden remains high in some Peruvian regions, especially in the Northeast Amazon rainforest state of Loreto and the tropical coastal state of Tumbes. Novel non-invasive diagnostic tools for malaria are being developed, and formative research in malaria-endemic areas with community members and health professionals who would potentially use these devices is vital for this process. This study aimed to examine the acceptability and feasibility of four new non-invasive malaria diagnostic tools in development in two regions of Peru with significant malaria burden.

methodsThe research team conducted focus group discussions and key informant interviews in Spanish to assess acceptability and ascertain questions and concerns regarding the non-invasive diagnostic tools. Focus group discussions included a range of community members (pregnant women, parents), professionals (health, education), and community leaders in Loreto. Vector control authorities and health professionals from Loreto, Tumbes, and Lima participated as key informants.

resultsParticipants were initially enthusiastic about all non-invasive diagnostic tools. However, as discussions proceeded, high enthusiasm remained for two devices that were easy to use, acceptable for the communities they were intended for, feasible to carry in remote areas, and did not require new supplies nor generate waste: the skin scan and the skin odour test. The breath and saliva tests were considered less hygienic. They were less acceptable to community members and health professionals due to concerns of disease transmission and other environmental and cultural concerns. Health professionals felt the finger scan test and the skin odour test would help triage community members in endemic sites and would be valuable in remote regions with difficult access to health facilities or laboratories.

conclusionsNovel non-invasive malaria diagnostic tools can be valuable in malaria-endemic settings. As manufacturers evaluate the efficacy and effectiveness of these non-invasive diagnostic tools, international recommendations should be created to ensure their agile integration into national malaria programmes.

Indexed as

Diagnostic Tests, RoutineMalariaPatient Acceptance of Health CareAdultFemaleFocus GroupsHumansInterviews as TopicMaleMiddle AgedPeruYoung AdultMalariaNon-invasive diagnostic tools

Identifiers

PMID39893463
PMCPMC11786561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.