Evidence map›Paper›PMID 39893340›Full record

ArticleAnnals of surgical oncology2025

Risk-Prediction Models for Clinical Decision-Making in Sarcoma Care: An International Survey Among Soft-Tissue Sarcoma Clinicians.

Anouk A Kruiswijk, Lisa A E Vlug, Ibtissam Acem, Ellen G Engelhardt, Alessandro Gronchi, Dario Callegaro, Rick L Haas, Robert J P van de Wal, Michiel A J van de Sande, Leti van Bodegom-Vos

Abstract read
In one paragraph

Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anouk A KruiswijkDepartment of Biomedical Data Sciences, Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands. a.a.kruiswijk@lumc.nl.ORCID http://orcid.org/0000-0003-4827-7466
Lisa A E VlugDepartment of Biomedical Data Sciences, Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands.
Ibtissam AcemDepartment of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Ellen G EngelhardtDivision of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Alessandro GronchiDepartment of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Dario CallegaroDepartment of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Rick L HaasDepartment of Radiotherapy, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Robert J P van de WalOrthopedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Michiel A J van de SandeOrthopedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Leti van Bodegom-VosDepartment of Biomedical Data Sciences, Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands.

Funding

KWF Kankerbestrijding 12642
6 · The paper itself

Abstract

introductionRisk prediction models (RPMs) are statistical tools that predict outcomes on the basis of clinical characteristics and can thereby support (shared) decision-making. With the shift toward personalized medicine, the number of RPMs has increased exponentially, including in multimodal sarcoma care. However, their integration into routine soft-tissue sarcoma (STS) care remains largely unknown. Therefore, we inventoried RPM use in sarcoma care during tumor board discussions and patient consultations as well as the attitudes toward the use of RPMs to support (shared) decision-making among STS clinicians. MATERIALS AND

methodsA 29-item survey was disseminated online to members of international sarcoma societies.

resultsThis study enrolled 278 respondents. Respectively, 68% and 65% of the clinicians reported using RPMs during tumor board discussions and/or patient consultations. During tumor board discussions, RPMs were used primarily to assess the potential benefits of (neo)adjuvant chemotherapy. During patient consultations, RPMs were used to predict patient prognosis upon request and to assist in decision-making regarding (neo)adjuvant therapies. The reliability of patient risk predicted by RPMs and the absence of guidelines regarding the use of RPMs were identified as barriers. Additionally, some clinicians questioned the applicability of estimates from RPMs to individual patients and expressed concerns about causing unnecessary anxiety when discussing prognostic outcomes.

conclusionsResponding STS clinicians frequently use RPMs to support decision-making about (neo)adjuvant therapies. However, they expressed concerns about the applicability of RPM estimates to individual patients and reported challenges in communicating prognostic outcomes with patients. These findings highlight the difficulties clinicians face when integrating RPMs into patient consultations.

Indexed as

Attitude of Health PersonnelClinical Decision-MakingDecision Making, SharedModels, StatisticalSarcomaFemaleHumansMalePrognosisRisk AssessmentSurveys and Questionnaires

Identifiers

PMID39893340
PMCPMC11882627

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.