Evidence map›Paper›PMID 39893326›Full record

ArticleSurgery today2025

Isoperistaltic hand-sewn side-to-side bowel primary anastomosis: a safe approach after bowel resection in children with neutropenic enterocolitis.

Mohammad Taher, Maged Elshafiey, Ahmed Refaat, Eman Nasr, Gehad Ahmed

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Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mohammad TaherDepartment of Surgical Oncology, National Cancer Institute, Cairo University, El Kasr El Aini St., Fom El-Khaleeg Sq., Cairo, 11796, Egypt. mohammed.taher@nci.cu.edu.eg.ORCID http://orcid.org/0000-0002-4678-9145
Maged ElshafieyDepartment of Surgical Oncology, National Cancer Institute, Cairo University, El Kasr El Aini St., Fom El-Khaleeg Sq., Cairo, 11796, Egypt.
Ahmed RefaatDepartment of Surgery, Children's Cancer Hospital Egypt (CCHE, 57357), Cairo, Egypt.
Eman NasrDepartment of Radio Diagnosis, National Cancer Institute, Cairo University, Cairo, Egypt.
Gehad AhmedDepartment of General Surgery, Faculty of Medicine, Helwan University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimWhether to perform primary anastomosis (PA) or create a stoma after bowel resection has always been a dilemma in pediatric cancer patients with neutropenic enterocolitis (NEC). The risk of leakage after PA must be weighed against the risk of stoma complications. We evaluated the outcomes of managing NEC patients with either PA or stoma and the utility of the isoperistaltic hand-sewn side-to-side anastomosis (ISSA) technique in PA. PATIENTS AND

methodsA retrospective study on all Children's Cancer Hospital Egypt patients with NEC who underwent surgical exploration at our hospital from 2008 to 2022.

resultsOf 153 children, 80 (52.3%) underwent PA and 73 (47.7%) underwent stoma formation. Among the 80 PA patients, 68 (85%) underwent ISSA, 9 (11.2%) end-to-end anastomosis (EEA), and 3 (3.8%) end-to-side anastomosis (ESA). The perioperative complication rate was 38/73 (52.1%) in the stoma patients and 35/80 (43.8%) in the PA patients. Leakage occurred in 6/68 (8.8%) ISSA patients, 5/9 (55.6%) EEA patients, and 1/3 (33.3%) of ESA patients.

conclusionsIn pediatric cancer patients with NEC, PA using ISSA after bowel resection is considered a better approach than any other anastomotic configuration.

Indexed as

Anastomosis, SurgicalEnterocolitis, NeutropenicIntestinesAdolescentAnastomotic LeakChildChild, PreschoolFemaleHumansInfantMalePostoperative ComplicationsRetrospective StudiesSafetySurgical StomasTreatment OutcomeNeutropenic enterocolitisPediatric cancerPrimary anastomosisSide-to-side isoperistaltic anastomosisStomaTyphlitis

Identifiers

PMID39893326
PMCPMC12339622

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