SynthesisEye (London, England)2025
Visual and patient-reported outcomes of an enhanced versus monofocal intraocular lenses in cataract surgery: a systematic review and meta-analysis.
Synthesis in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of visual outcomes of enhanced monofocal versus conventional monofocal intraocular lenses: a meta-analysis of randomized controlled trials.International ophthalmology · 2026Pooled it
- Comparison of visual performance among three higher-order aspheric enhanced monofocal intraocular lenses and a standard aspheric monofocal lens.Journal of cataract and refractive surgery · 2025Trial
- Extended Depth-of-Focus Intraocular Lens Based on Aberration-Neutral Technique.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Intermediate Visual Performance of Clareon Versus Eyhance Enhanced Monofocal Intraocular Lenses.Diagnostics (Basel, Switzerland) · 2026Article
- Monofocal intraocular lens based on the Bessel principle for improved intermediate vision: a comparative assessment.BMC ophthalmology · 2026Article
- Objective assessment of accommodation with an accommodative intraocular lens: Development of methodology and case report.Zeitschrift fur medizinische Physik · 2026Article
- Age-stratified comparison of visual function between eyes with an enhanced monofocal intraocular lens and phakic eyes.Japanese journal of ophthalmology · 2026Article
- Advances and Challenges in Sulcus-Implanted Intraocular Lenses: A Comprehensive Narrative Review.Ophthalmology and therapy · 2026Review
- Evaluation of visual outcomes, optical quality, and patient satisfaction with a novel monofocal intraocular lens.BMC ophthalmology · 2026Article
- The Effect of the Capsular Bag on the Optical Performance of an IOL Measured in an Ex Vivo Model.Investigative ophthalmology & visual science · 2026Article
- Modern Hydrophobic Acrylic Intraocular Lens Incorporating HEMA: Three-Month Refractive and Visual Outcomes.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Visual, Refractive, and Patient-Reported Outcomes Following Bilateral Implantation of an Enhanced Monofocal IOL: An Exploratory Comparison of Achieved Mini-Monovision and Bilateral Emmetropia.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- 12-month clinical outcomes of the Evolux™ extended monofocal intraocular lens following cataract surgery.BMC ophthalmology · 2025Article
- Navigating the Lens Labyrinth: A Practical Approach to Intraocular Lens Classification and Selection.Ophthalmology and therapy · 2025Article
- Clinical Outcomes and Optical Bench Analysis of a Novel Enhanced Monofocal Intraocular Lens.Life (Basel, Switzerland) · 2025Article
- Effects of enhanced monofocal intraocular lenses on intermediate and near vision.Eye (London, England) · 2025Article
- A comparative study and review of visual outcomes with enhanced versus standard monofocal intraocular lenses following cataract surgery.Medical hypothesis, discovery & innovation ophthalmology journal · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the functional outcomes achieved with new enhanced monofocal intraocular lenses (IOLs) is crucial for adequately managing patient expectations. This study evaluated visual and patient-reported outcomes of an enhanced range of field IOL versus other monofocal IOLs in cataract patients. A systematic review and meta-analysis, pre-registered on PROSPERO (CRD42024561611), included studies from Medline (PubMed), Embase (Ovid), and trial registries (2019-2024) focused on binocular cataract surgeries with various IOL models. Primary outcomes assessed were monocular distance-corrected visual acuities (CDVA, DCIVA, DCNVA), defocus curves, and contrast sensitivity; secondary measures included binocular visual acuities and patient-reported outcomes such as spectacle independence and photic phenomena. Out of 31 studies (8 randomized clinical trials, 23 case series), high-certainty evidence indicated no significant difference in CDVA between enhanced and conventional IOLs. However, enhanced IOLs demonstrated better intermediate (DCIVA: -0.11 logMAR, CI 95%: -0.13 to -0.10) and near (DCNVA: -0.12 logMAR, CI 95%: -0.17 to -0.07) visual acuities, supported by defocus curves, though with lower-certainty evidence. No significant differences were observed in contrast sensitivity or photic phenomena, and evidence for positive dysphotopsia was moderate to low. Enhanced IOLs significantly favored intermediate-distance spectacle independence, with an odds ratio of 7.85 (CI 95%: 4.08-15.09), though no differences were observed for distance spectacle independence. Near-distance spectacle independence also favored enhanced IOLs, though with low-certainty evidence. In summary, enhanced IOLs provide improved intermediate and near visual acuities compared to conventional monofocal IOLs, though further studies are needed to confirm outcomes in contrast sensitivity and patient-reported outcomes across various enhanced monofocal IOLs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.