Evidence map›Paper›PMID 39893232›Full record

ArticleScientific reports2025

Exploring the feasibility and clinical impact of ultrasound microvascular flow imaging in detecting brain injury in hyperbilirubinemia neonates.

Shuang He, Meiyu Wang, Man Zhu, Min Zhang, Xueni He, Xiang Jiang, Shu Tang, Zhaoxia Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuang He *Department of Ultrasound, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Children's Hospital of Chongqing Medical University, Lianglukou Street, Yuzhong District, Chongqing, China.
Meiyu Wang *Department of Pediatrics, Shulan (Jinan) Hospital, Jinan, China.
Man ZhuDepartment of Ultrasound, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Children's Hospital of Chongqing Medical University, Lianglukou Street, Yuzhong District, Chongqing, China.
Min ZhangDepartment of Ultrasound, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Children's Hospital of Chongqing Medical University, Lianglukou Street, Yuzhong District, Chongqing, China.
Xueni HeDepartment of Ultrasound, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Children's Hospital of Chongqing Medical University, Lianglukou Street, Yuzhong District, Chongqing, China.
Xiang JiangDepartment of Ultrasound, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Children's Hospital of Chongqing Medical University, Lianglukou Street, Yuzhong District, Chongqing, China.
Shu TangKey Laboratory of Computer Network and Communications Technology, Chongqing University of Posts and Telecommunications, Chongqing, China. tangshu@cqupt.edu.cn.
Zhaoxia WangDepartment of Ultrasound, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Children's Hospital of Chongqing Medical University, Lianglukou Street, Yuzhong District, Chongqing, China. zhaoxia_wang103@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal hyperbilirubinemia is a prevalent condition during the neonatal period, and in severe instances, it can result in brain damage accompanied by irreversible neurological consequences. Therefore, early detection and intervention are paramount. This research aimed to detect early-stage brain damage resulting from neonatal hyperbilirubinemia through the application of two-dimensional cranial ultrasound and microvascular blood flow (MV-Flow) imaging techniques. Clinical data, along with gray-scale and microvascular ultrasound images of the basal ganglia, were collected from 85 neonates (hyperbilirubinemia group vs. non-hyperbilirubinemia group: 51 vs. 34). The Globus Pallidus to Putamen (G/P) ratio and the vascular index (VI

Indexed as

Brain InjuriesCerebrovascular CirculationHyperbilirubinemia, NeonatalMicrocirculationUltrasonographyFeasibility StudiesFemaleHumansImage Processing, Computer-AssistedInfant, NewbornInfant, PrematureRetrospective StudiesCranial UltrasoundHyperbilirubinemiaMV-FlowNeonatal

Identifiers

PMID39893232
PMCPMC11787357

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.