Evidence map›Paper›PMID 39893202›Full record

ArticleNPJ vaccines2025

A systematised review and evidence synthesis on the broader societal impact of vaccines against Salmonella.

Ezgi Dilek Demirtas, Rosanna Barnard, Jungseok Lee, Mark Jit

Abstract read
In one paragraph

Article in NPJ vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Poultry Food Assess Risk Model forFoods (Basel, Switzerland) · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ezgi Dilek DemirtasDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.ORCID http://orcid.org/0009-0008-5183-8651
Rosanna BarnardDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Jungseok LeeInternational Vaccine Institute, Seoul, South Korea.
Mark JitDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK. mark.jit@lshtm.ac.uk.ORCID http://orcid.org/0000-0001-6658-8255

Funding

Wellcome Trust
6 · The paper itself

Abstract

Vaccines against Salmonella Typhi are available, while vaccines against invasive non-typhoidal Salmonella are in development. Investments in vaccine development and introduction need to be informed by a full value of vaccines assessment, including consideration of broader societal impacts of salmonellae disease. We reviewed literature on these broader impacts in low- and middle-income countries to inform a conceptual framework. We found 16 studies relevant to Salmonella, but only one study on non-typhoidal Salmonella. Despite variations in study design, methodology, and study quality, salmonellae infections were largely associated with negative broader societal impacts, including detriments in childhood physical development (very weak association), childhood educational development (strong to very strong association), household security (moderate association), public health spending (moderate association), and national income (moderate to strong association). Study quality was low for all impacts except childhood physical development. There were no studies measuring economic impact of antimicrobial resistance, changes in household behaviour or health inequalities.

Identifiers

PMID39893202
PMCPMC11787315

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.