Evidence map›Paper›PMID 39892935›Full record

ReviewClinics in laboratory medicine2025

Molecular Diagnostics for Invasive Molds: From Lab to Bedside.

Alisse Hannaford, Ruben Alfonso Hernandez-Acosta, Jessica S Little, Jeffrey I Campbell, Zoe F Weiss, Amy C Sherman

Abstract readReview
In one paragraph

Review in Clinics in laboratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Azole-ResistantJournal of fungi (Basel, Switzerland) · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alisse HannafordDepartment of Internal Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA; Department of Internal Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA, USA.
Ruben Alfonso Hernandez-AcostaDepartment of Internal Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.
Jessica S LittleDepartment of Internal Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA, USA.
Jeffrey I CampbellSection of Pediatric Infectious Diseases, Boston Medical Center, Boston, MA, USA.
Zoe F WeissDepartment of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA, USA.
Amy C ShermanDepartment of Internal Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: acsherman@bwh.harvard.edu.

Funding

INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
The relationship between HIV exposure, contact networks, and TB in children under 5 years oldK23AI186597 · NIAID · BOSTON MEDICAL CENTER · PI Jeffrey Ian Campbell · 2024 to 2026
$574k
NIAID NIH HHS K23 AI186597NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

This review highlights the current state of molecular diagnostic modalities to detect invasive fungal infections, with a focus on molds in immunocompromised children and adults. Molecular diagnostics may also be utilized to detect antifungal drug resistance. Although both pathogen-specific and pathogen-agnostic assays may be beneficial in more rapidly identifying fungal infection with less invasive sampling in high-risk populations, the clinical implementation and interpretation of these tests must consider several important factors, including anatomic site and type of specimen, host characteristics, use of antifungal prophylaxis, and timing of specimen collection.

Indexed as

FungiInvasive Fungal InfectionsMolecular Diagnostic TechniquesHumansFungal diagnosticsImmunocompromised hostInvasive fungal diseaseMetagenomic sequencingMolecular diagnosticsMycosesPCR

Identifiers

PMID39892935
PMCPMC11921983

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.