Evidence map›Paper›PMID 39892180›Full record

SynthesisValue in health regional issues2025

Utility Values of Health Status in Gastric Cancer: A Systematic Review.

Cristian Gonzalez, Manuel Espinoza, Matías Libuy, Francisca Crispi, Arnoldo Riquelme, Fernando Alarid-Escudero, Gonzalo Latorre, Margarita Pizarro, Cristóbal Cuadrado

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Value in health regional issues, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cristian GonzalezEscuela de Salud Pública, Universidad de Chile, Santiago de Chile, RM, Chile.
Manuel EspinozaDepartamento Salud Pública, Pontificia Universidad Católica de Chile, Santiago de Chile, RM, Chile; Centro de Prevención y Control de Cáncer (CECAN), Santiago de Chile, RM, Chile.
Matías LibuyEscuela de Salud Pública, Universidad de Chile, Santiago de Chile, RM, Chile.
Francisca CrispiEscuela de Salud Pública, Universidad de Chile, Santiago de Chile, RM, Chile.
Arnoldo RiquelmePontificia Universidad Católica de Chile, Faculty of Medicine, School of Medicine, Department of Gastroenterology, Santiago de Chile, RM, Chile.
Fernando Alarid-EscuderoDepartment of Health Policy, School of Medicine and Center for Health Policy, Freeman Spogli Institute, Stanford University, Stanford, CA, USA.
Gonzalo LatorrePontificia Universidad Católica de Chile, Faculty of Medicine, School of Medicine, Department of Gastroenterology, Santiago de Chile, RM, Chile.
Margarita PizarroPontificia Universidad Católica de Chile, Faculty of Medicine, School of Medicine, Department of Gastroenterology, Santiago de Chile, RM, Chile.
Cristóbal CuadradoEscuela de Salud Pública, Universidad de Chile, Santiago de Chile, RM, Chile; Centro de Prevención y Control de Cáncer (CECAN), Santiago de Chile, RM, Chile. Electronic address: ccuadrado@uchile.cl.

Funding

Comparative modeling of gastric cancer health drivers and prevention in the US and globallyU01CA265729 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HUR, CHIN, YEH, JENNIFER M. · 2021 to 2025
$4.1M
NCI NIH HHS U01 CA265729
6 · The paper itself

Abstract

objectivesGastric cancer (GC) imposes a significant burden of disease globally. Multiple treatments are available but are associated with high costs and potentially detrimental effects on quality of life. The utility values of health status are measures of patient preference over quality of life, which are increasingly used for health and economic decision-making. Currently, there is little systematized information on the utility values for different stages of GC. This systematic review synthesizes and meta-analyses the literature on GC utilities.

methodsA search was conducted in PubMed, Embase, MEDLINE, and Cochrane Library for studies reporting utility values calculated using direct and indirect methods. Information from the selected studies was extracted and appraised, and meta-analyses of utility values based on GC health states were performed.

resultsTwelve studies involving 4585 patients were included. Random-effects meta-analysis estimates showed a mean utility of 0.77 (95% CI 0.7-0.85) for stage I, 0.75 (95% CI 0.65-0.85) for stage II, 0.70 (95% CI 0.63-0.96) for stage III, and 0.64 (95% CI 0.56-0.32) for stage IV. All estimates showed considerable heterogeneity.

conclusionsOur study provides an updated overview of the literature on utility values in GC and presents a discussion of the relevance of GC stages for its analysis. Decision-makers should consider patients' preferences in the proposal of policies and clinical decisions.

Indexed as

Health StatusQuality of LifeStomach NeoplasmsHumansPatient Preferenceeconomic evaluationEQ-5Dgastric cancerhealth-state utility values

Identifiers

PMID39892180
PMCPMC12225718

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.