Evidence map›Paper›PMID 39891958›Full record

ArticleRedox biology2025

Protective role of vitamin D receptor against mitochondrial calcium overload from PM

Mengqiu Lu, Zishun Zhan, Dan Li, Hengbing Chen, Aimei Li, Jing Hu, Zhijun Huang, Bin Yi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. CaMaterials today. Bio · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengqiu LuDepartment of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Clinical Research Center for Critical Kidney Disease in Hunan Province, China.
Zishun ZhanDepartment of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Clinical Research Center for Critical Kidney Disease in Hunan Province, China; Center for Experimental Medicine, The Third Xiangya Hospital of Central South University, Changsha, China; Department of Cardiology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Dan LiDepartment of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Clinical Research Center for Critical Kidney Disease in Hunan Province, China.
Hengbing ChenDepartment of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Clinical Research Center for Critical Kidney Disease in Hunan Province, China.
Aimei LiDepartment of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Clinical Research Center for Critical Kidney Disease in Hunan Province, China.
Jing HuDepartment of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Clinical Research Center for Critical Kidney Disease in Hunan Province, China.
Zhijun HuangDepartment of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Furong Laboratory, Changsha, Hunan, China. Electronic address: huangzj@csu.edu.cn.
Bin YiDepartment of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Clinical Research Center for Critical Kidney Disease in Hunan Province, China. Electronic address: yibin2008@csu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis research explores the consequences of being exposed to PM

methodsAnimal models of chronic PM

resultsPM

conclusionThis study shows that activating Vitamin D-VDR signaling shields the kidneys from PM

Indexed as

CalciumKidney TubulesMitochondriaParticulate MatterReceptors, CalcitriolAnimalsCalcium ChannelsCell LineHumansMaleMiceOxidative StressCalciumCalcium Channelsmitochondrial calcium uniporterParticulate MatterReceptors, CalcitriolFine particulate matterKidney injuryMCUMitochondrial calcium overloadOxidative stressVDR

Identifiers

PMID39891958
PMCPMC11836507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.