Evidence map›Paper›PMID 39891522›Full record

ArticleBioengineered2025

A novel mannan-specific chimeric antigen receptor M-CAR redirects T cells to interact with

Júlia Garcia Guimarães, Gabriela Yamazaki de Campos, Michele Procópio Machado, Patrícia Kellen Martins Oliveira Brito, Thaila Fernanda Dos Reis, Gustavo Henrique Goldman, Patricia Vianna Bonini Palma, Thais Fernanda de Campos Fraga-Silva, Daniela Cardoso Umbelino Cavallin, James Venturini and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Júlia Garcia GuimarãesDepartment of Cellular and Molecular Biology, Ribeirao Preto Medical School, University of São Paulo, São Paulo, Brazil.
Gabriela Yamazaki de CamposDepartment of Cellular and Molecular Biology, Ribeirao Preto Medical School, University of São Paulo, São Paulo, Brazil.
Michele Procópio MachadoDepartment of Cellular and Molecular Biology, Ribeirao Preto Medical School, University of São Paulo, São Paulo, Brazil.
Patrícia Kellen Martins Oliveira BritoDepartment of Cellular and Molecular Biology, Ribeirao Preto Medical School, University of São Paulo, São Paulo, Brazil.
Thaila Fernanda Dos ReisRibeirão Preto Pharmaceutical Sciences School, University of São Paulo, São Paulo, Brazil.
Gustavo Henrique GoldmanRibeirão Preto Pharmaceutical Sciences School, University of São Paulo, São Paulo, Brazil.
Patricia Vianna Bonini PalmaCenter for Cell-Based Therapy, Regional Blood Center of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.
Thais Fernanda de Campos Fraga-SilvaInstitute of Biological and Health Sciences, Federal University of Alagoas, Maceió, Brazil.
Daniela Cardoso Umbelino CavallinDepartment of Clinical Analysis, School of Pharmaceutical Sciences in Araraquara, Sao Paulo State University, São Paulo, Brazil.
James VenturiniFaculty of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Brazil.
Thiago Aparecido da SilvaDepartment of Cellular and Molecular Biology, Ribeirao Preto Medical School, University of São Paulo, São Paulo, Brazil.ORCID 0000-0001-5017-6539

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive fungal infections (IFIs) are responsible for elevated rates of morbidity and mortality, causing around of 1.5 million deaths annually worldwide. One of the main causative agents of IFIs is

Indexed as

BioengineeringCandida albicansInvasive Fungal InfectionsReceptors, Chimeric AntigenRhizopus oryzaeT-LymphocytesCandidiasisHEK293 CellsHumansJurkat CellsLymphocyte ActivationMucormycosisReceptors, Chimeric Antigencandida sppChimeric Antigen Receptorinvasive fungal infectionjurkat cellsmannanrhizopus oryzae

Identifiers

PMID39891522
PMCPMC11792852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.