Evidence map›Paper›PMID 39891258›Full record

ArticleJournal of nanobiotechnology2025

Nanocarriers boost non-systemic fluazinam transportation in plants and microbial community enrichment in soil.

Wenhui Xiao, Jiang Du, Yuxin Zheng, Shanshan Chen, Zhanyun Liu, Fengping Chen, Feng Liu, Beixing Li, Xili Liu, Can Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenhui Xiao *Department of Plant Pathology, China Agricultural University, Beijing, 100193, China.
Jiang Du *Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect Pests, College of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, China.
Yuxin ZhengDepartment of Plant Pathology, China Agricultural University, Beijing, 100193, China.
Shanshan ChenDepartment of Plant Pathology, China Agricultural University, Beijing, 100193, China.
Zhanyun LiuDepartment of Plant Pathology, China Agricultural University, Beijing, 100193, China.
Fengping ChenState Key Laboratory of Agricultural and Forestry Biosecurity & Key Lab of Biopesticide and Chemical Biology, Ministry of Education, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, Fujian, China.
Feng LiuShandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect Pests, College of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, China.
Beixing LiShandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect Pests, College of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, China. beixingli@sdau.edu.cn.
Xili LiuDepartment of Plant Pathology, China Agricultural University, Beijing, 100193, China. seedling@cau.edu.cn.
Can ZhangDepartment of Plant Pathology, China Agricultural University, Beijing, 100193, China. czhang@cau.edu.cn.

Funding

National Key Research and Development Program of the Ministry of Science and Technology No. 2022YFD1400900the project of National Key Laboratory of Green Pesticide / Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University No. SKL-GPL-KF-202409
6 · The paper itself

Abstract

Utilizing nanotechnology for pesticide delivery can enhance their uptake and distribution in plants, thereby boosting pesticide efficiency. Fluazinam, a highly effective broad-spectrum fungicide with unique mode of action, is hindered by its poor systemic conductivity, limiting its field control efficacy. In this study, fluazinam-loaded nanocapsules were developed, which exhibited significantly higher inhibitory activity against various Phytophthora species compared to the commercial suspension concentrate. Notably, the nanocapsules demonstrated pronounced effects on reducing ATP content in Phytophthora capsici and effectively controlled pepper blight and cucumber downy mildew. Tracking the distribution of fluorescein isothiocyanate (FITC) fluorescein-labeled fluazinam nanocapsules revealed their presence in roots seven days after treatment. High-performance liquid chromatography (HPLC) analysis confirmed the easy absorption and transport of fluazinam nanocapsules by pepper plants. Moreover, treatment with fluazinam nanocapsules significantly increased the expression of two exocytosis genes, FACP and RABF2a, in pepper tissues. Lastly, fluazinam nanocapsules were found to enhance the relative abundance of beneficial bacteria in the soil microbial community. This study presents a promising approach to enhance the upward transport capability of non-systemic pesticides, offering novel insights into their application and improved efficacy.

Indexed as

Drug CarriersFungicides, IndustrialNanocapsulesSoil MicrobiologyCapsicumCucumis sativusPhytophthoraPlant DiseasesPlant RootsSoilDrug CarriersFungicides, IndustrialNanocapsulesSoilMicrobial communitiesNanocapsulesNon-systemic pesticidesSoil applicationUpward conduction

Identifiers

PMID39891258
PMCPMC11783915

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.