Evidence map›Paper›PMID 39891177›Full record

ArticleBMC musculoskeletal disorders2025

Global burden of neck pain and its gender and regional inequalities from 1990 - 2021: a comprehensive analysis from the Global Burden of Disease Study 2021.

Haifeng Wu, Yue Li, Congying Zou, Weidong Guo, Feng Han, Guoshun Huang, Lin Sun

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Cognitive-behavioural treatment for neck pain.The Cochrane database of systematic reviews · 2026
    Article
  4. Comparison of the short-term effects of Mulligan and Maitland mobilisation techniques combined with home-based exercise for non-specific neck pain: A randomised controlled trial.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2026
    Article
  5. Global, regional, and national burden of disease in neck pain: statistical analysis of incidence, prevalence, and DALYS, with projections to 2036.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  6. [Analysis of current status and trends of disease burden of neck pain in China from 1990 to 2023].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haifeng Wu *Department of Orthopedic Surgery, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Yue Li *Department of Orthopedic Surgery, General Hospital of Tisco, Yingxin Road 7#, Jiancaoping District, Taiyuan, Shanxi Province, 030008, China.ORCID http://orcid.org/0000-0001-6924-8969
Congying Zou *Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gong Ti Nan Lu, Chaoyang District, Beijing, 100020, China.ORCID http://orcid.org/0009-0001-5268-3638
Weidong GuoDepartment of Orthopedic Surgery, General Hospital of Tisco, Yingxin Road 7#, Jiancaoping District, Taiyuan, Shanxi Province, 030008, China.
Feng HanDepartment of Orthopedic Surgery, General Hospital of Tisco, Yingxin Road 7#, Jiancaoping District, Taiyuan, Shanxi Province, 030008, China.
Guoshun HuangDepartment of Orthopedic Surgery, General Hospital of Tisco, Yingxin Road 7#, Jiancaoping District, Taiyuan, Shanxi Province, 030008, China.
Lin SunDepartment of Orthopedic Surgery, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, 030032, China. sunlin_9999@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeck pain is a growing public health concern, no recent research has comprehensively examined its incidence and years lived with disability (YLDs) across different regions and genders. For the first time, this study aims to provide the most recent estimates on the global burden of neck pain between 1990 and 2021 obtained from the 2021 global burden of disease (GBD) database, focusing on regional and gender inequalities. We also predict future trends, highlighting its increasing impact on public health. MATERIALS AND

methodsThe study was conducted retrospectively using publicly available data from the GBD 2021 database, acquired on August 20, 2024. The incidence and burden of neck pain were assessed using DisMod-MR 2.1. Data on incidence and years lived with disability (YLDs) rates per 100,000 people were obtained for countries, regions, ages, and sexes globally.

resultsIn 2021, the global age-standardized rates for incidence, and YLDs of neck pain per 100,000 population was 519 (95% uncertainty interval, 408-633), and 242 (163-343) per 100,000 population, respectively. Joinpoint regression showed both rates demonstrated an overall increasing trend from 1990 to 2021 worldwide. Projections suggest a slight decline in these rates for the coming years. Women consistently showed a higher burden than men across all age groups. Regional analyses indicated that the Islamic Republic of Iran had the highest rates, whereas New Zealand had the lowest. Negative correlations were observed between the Estimated Annual Percentage Change (EAPC) and both the age-standardized rates and the Sociodemographic Index (SDI). Low-SDI countries generally exhibited higher incidence and YLDs rates, whereas high-SDI countries maintained higher YLDs rates despite relatively lower incidence rates.

conclusionThe global burden of neck pain increased between 1990 and 2021, but future projections indicate a potential mild decrease. Gender and regional inequalities persist, underscoring the need for targeted policy interventions focusing on women and low-SDI regions to alleviate the burden of neck pain.

Indexed as

Global Burden of DiseaseHealth Status DisparitiesNeck PainAdolescentAdultAgedChildCost of IllnessDisability-Adjusted Life YearsFemaleGlobal HealthHumansIncidenceMaleMiddle AgedRetrospective StudiesIncidenceInequalitiesNeck painPublic health

Identifiers

PMID39891177
PMCPMC11786424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.