ArticleBMC pulmonary medicine2025
Global, regional, and national epidemiology of allergic diseases in children from 1990 to 2021: findings from the Global Burden of Disease Study 2021.
Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comprehensive exercise recommendations for pediatric asthma: an evidence synthesis.World journal of pediatrics : WJP · 2026Pooled it
- Causal association between allergic diseases and short stature: a mendelian randomization study revealing the potential mediating role of inflammatory proteins.Jornal de pediatria · 2026Article
- Multi-omics causal inference of childhood asthma triggered by ambient particulate matter.ERJ open research · 2026Article
- Climate change, environmental exposures, and pediatric asthma exacerbations: air pollution, temperature, and relative humidity.Pediatric research · 2026Review
- Child characteristics, household, and home environmental factors associated with eczema: a cross-sectional study.European journal of pediatrics · 2026Article
- Pear Polysaccharide Alleviates Asthma Symptoms in Association With a Ferroptosis-Related Biomarker Network: An Integrated Bioinformatics and Experimental Study.Molecular nutrition & food research · 2026Article
- Aeroallergen Sensitization Status in West China from 2024 to 2025.Journal of clinical medicine · 2026Article
- Folic Acid Level of Children with Atopy/Asthma and Children Without Chronic Allergic Disease-Should We Consider Nutritional Fortification?Nutrients · 2026Article
- Asthma knowledge and health-promoting behaviours among schoolchildren in Oman: a cross-sectional study.BMC public health · 2026Article
- Prediction of allergic disease trajectories from birth up to adolescence.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
- Allergic reactions in systemic lupus erythematosus: From pathogenic pathways to clinical practice.Asia Pacific allergy · 2026Review
- Serum Eosinophil Cationic Protein (ECP) as a Biomarker for Distinguishing Pediatric Allergic Airway Diseases.International journal of molecular sciences · 2026Article
- Distributional characteristics analysis of aeroallergens among children With allergic respiratory diseases in Sichuan province, China.Frontiers in pediatrics · 2026Article
- From gut microbiota dysbiosis to immune dysregulation: pathogenic mechanisms and emerging therapeutic perspectives in pediatric asthma.Frontiers in immunology · 2026Review
- Current challenges in allergic diseases and computational solutions towards personalized medicine.Frontiers in allergy · 2026Review
- Potential clinical benefits of probiotics in pediatric allergic rhinitis: a systematic review and network meta-analysis.Frontiers in pediatrics · 2026Review
- Relationship between perfluoroalkyl substance exposure and immunoglobulin E among Korean adults from Korean National Environmental Health Survey cycle 4 (2018-2020): a cross-sectional study.Frontiers in public health · 2026Article
- Digital health in allergy care: current practices, evidence, and future prospects.Frontiers in allergy · 2026Review
- Sensitization to 19 allergen sources in 2,124 children in Kashi Prefecture, China: a single-center cross-sectional retrospective study.Frontiers in allergy · 2026Article
- The prevalence of outgrowing non-priority legume allergies in children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma and atopic dermatitis (AD) represent significant global health challenges in children. This study aimed to investigate trends in incidence, prevalence, and disability-adjusted life years (DALYs) for childhood asthma and AD from 1990 to 2021.
methodsThe study utilized information from the Global Burden of Disease (GBD), Injuries, and Risk Factors Study 2021. The sample size for this study consisted of children with asthma or AD between the ages of 0 and 14. From 1990-2021, we calculated asthma and AD's age-standardized incidence, prevalence, and DALYs by area, age, sex, and socio-demographic index.
resultsIn 2021, global childhood asthma prevalence reached 95.7 million cases (age-standardized rate: 4,758 per 100,000), with the Low SDI region recording 25.4 million cases. For AD, global prevalence was 72.4 million cases (age-standardized rate: 3,600 per 100,000), predominantly in Middle SDI regions (19.7 million cases). Between 1990 and 2021, age-standardized incidence rates decreased for both conditions. Geographic variations were notable: High-income North America showed the highest asthma incidence, while Western Europe led in AD prevalence. The global burden of asthma-related DALYs declined from 6.9 million in 1990 to 4.6 million in 2021, with significant regional disparities.
conclusionsDespite decreasing age-standardized rates, childhood asthma and AD continue to pose substantial health burdens globally, with marked variations across regions and socioeconomic strata. These findings emphasize the need for targeted, region-specific interventions.
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