ArticleBMC public health2025
Gender differences in associations between obesity and hypertension, diabetes, dyslipidemia: evidence from electronic health records of 3.5 million Chinese senior population.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Multiomics Insights Linking Personal Care Products Exposure to Serum Lipid Profiles in Older Adults: The China BAPE Study.Environmental health perspectives · 2026Article
- A Cross-Sectional Study of Sex-Specific Associations of Renin and Electrolytes on the Development of Hypertension.Journal of clinical medicine · 2026Article
- Comparison of the association and discriminatory ability of CVAI, LAP, CI, and AVI for type 2 diabetes in Chinese adults aged ≥ 50 years: a sex-specific analysis.Frontiers in endocrinology · 2026Article
- High-Fat Diet and Metabolic Diseases: A Comparative Analysis of Sex-Dependent Responses and Mechanisms.International journal of molecular sciences · 2025Review
- Patterns of multimorbidity across obesity severity and fat distribution in Anhui, China: a community-based study.Frontiers in endocrinology · 2025Article
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Abstract
backgroundObesity has been arousing a critical public health issue, and posting threats to senior population. We aimed to explore gender differences in associations between general/central obesity (body mass index/waist circumference) and hypertension, diabetes, dyslipidemia based on electronic health records of 3.5 million Chinese senior population over 65 years.
methods3571189 electronic health records of Chinese senior population were collected from platform of Zhejiang provincial Basic Public Health Services Project. Sociodemographic characteristics, behavioral lifestyle, physical data, and biochemical indices were included in the research. Multivariate logistic regression models and restricted cubic spline models were used to explore associations between obesity and diseases.
results7.7% (5.3% for male, 9.7% for female) senior population were having general obesity, and 31.8% (25.2% for male, 37.4% for female) of them had central obesity. 48.0% (46.0% for male, 49.7% for female), 14.0% (12.3% for male, 15.5% for female), and 58.9% (51.6% for male, 65.2% for female) senior population were having hypertension, diabetes, and dyslipidemia, respectively. 37.9% (29.5% for male, 45.1% for female) and 33.7% (28.1% for male, 38.5% for female) senior population were having abnormal TC and TG, respectively. General obesity and central obesity strongly and negatively associated with hypertension [OR = 2.61 (95%CI: 2.58-2.63), and 2.20 (95%CI: 2.18-2.21)], diabetes [OR = 1.33 (95%CI: 1.31-1.35), and 1.56 (95%CI: 1.54-1.57)], and dyslipidemia [OR = 1.66 (95%CI: 1.64-1.68), and 1.84 (95%CI: 1.83-1.85)] based on existing obesity standards. Male population with BMI higher than 28.7 kg/m
conclusionsSenior population were more likely to have central obesity over general obesity, and nearly half of them were having hypertension and dyslipidemia. Obesity negatively and strongly associated with chronic diseases in senior population, yet general obesity exerted more impact on hypertension, whereas central obesity exerted more impact on diabetes and dyslipidemia. Female population with obesity were in higher risk than male having hypertension, diabetes, and dyslipidemia. We recommended senior population control BMI lower than 28.7 kg/m
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