Evidence map›Paper›PMID 39890897›Full record

ArticleScientific reports2025

Automated strabismus detection and classification using deep learning analysis of facial images.

Mahsa Yarkheir, Motahhareh Sadeghi, Hamed Azarnoush, Mohammad Reza Akbari, Elias Khalili Pour

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  10. Artificial intelligence in ophthalmology: opportunities, challenges, and ethical considerations.Medical hypothesis, discovery & innovation ophthalmology journal · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahsa Yarkheir *Biomedical Engineering Department, Amirkabir University of Technology (Tehran Polytechnic), 424 Hafez, P.O. Box:15875-4413, Tehran, Iran.
Motahhareh Sadeghi *Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Qazvin Street, Box: 14176-13151, Tehran, Iran.
Hamed AzarnoushBiomedical Engineering Department, Amirkabir University of Technology (Tehran Polytechnic), 424 Hafez, P.O. Box:15875-4413, Tehran, Iran. hamed.azarnoush@gmail.com.
Mohammad Reza AkbariFarabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Qazvin Street, Box: 14176-13151, Tehran, Iran.
Elias Khalili PourFarabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Qazvin Street, Box: 14176-13151, Tehran, Iran. ekhalilipour@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strabismus, or eye misalignment, is a common condition affecting individuals of all ages. Early detection and accurate classification are essential for proper treatment and avoiding long-term complications. This research presents a new deep-learning-based approach for automatically identifying and classifying strabismus from facial images. The proposed methodology leverages Convolutional Neural Networks (CNNs) to achieve high accuracy in both binary (strabismus vs. normal) and multi-class (eight-class deviation angle for esotropia and exotropia) classification tasks. The dataset for binary classification consisted of 4,257 facial images, including 1,599 normal cases and 2,658 strabismus cases, while the multi-class classification involved 480 strabismic and 142 non-strabismic images. These images were labeled based on ophthalmologist measurements using the Alternate Prism Cover Test (APCT) or the Modified Krimsky Test (MK). Five-fold cross-validation was employed, and performance was evaluated using sensitivity, accuracy, F1-score, and recall metrics. The proposed deep learning model achieved an accuracy of 86.38% for binary classification and 92.7% for multi-class classification. These results demonstrate the potential of our approach to assist healthcare professionals in early strabismus detection and treatment planning, ultimately improving patient outcomes.

Indexed as

Deep LearningFaceImage Processing, Computer-AssistedStrabismusChildFemaleHumansMaleNeural Networks, Computer

Identifiers

PMID39890897
PMCPMC11785772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.