Evidence map›Paper›PMID 39890756›Full record

GuidelineInternational journal of hematology2025

Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024: part 4-trauma, burn, obstetrics, acute pancreatitis/liver failure, and others.

Mineji Hayakawa, Yoshinobu Seki, Takayuki Ikezoe, Kazuma Yamakawa, Kohji Okamoto, Shigeki Kushimoto, Yuichiro Sakamoto, Yuki Itagaki, Yuki Takahashi, Hiroyasu Ishikura and 26 more

Erratum issuedAbstract readPractice GuidelineSystematic Review
PubMed Publisher
In one paragraph

Guideline in International journal of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

36 authors.

Mineji HayakawaEmergency and Critical Care Center, Hokkaido University Hospital, North 14-West5, Kita-Ku, Sapporo, 060-8648, Japan. mineji@dream.com.ORCID http://orcid.org/0000-0001-8341-7626
Yoshinobu SekiDepartment of Hematology, Niigata University Medical and Dental Hospital, Niigata, Japan.
Takayuki IkezoeDepartment of Hematology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Kazuma YamakawaDepartment of Emergency and Critical Care Medicine, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Kohji OkamotoDepartment of Surgery, Kitakyushu City Yahata Hospital, Kitakyushu, Japan.
Shigeki KushimotoDivision of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yuichiro SakamotoDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Yuki ItagakiEmergency and Critical Care Center, Hokkaido University Hospital, North 14-West5, Kita-Ku, Sapporo, 060-8648, Japan.
Yuki TakahashiEmergency and Critical Care Center, Hokkaido University Hospital, North 14-West5, Kita-Ku, Sapporo, 060-8648, Japan.
Hiroyasu IshikuraDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Toshihiko MayumiDepartment Intensive Care, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Japan.
Toshihisa TamuraDepartment of Surgery 1, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Kenji NishioDepartment of General Medicine, Uda City Hospital, Uda, Japan.
Yu KawazoeDepartment of Emergency Medicine, Sendai Medical Center, Sendai, Japan.
Ayami ShigenoDepartment Intensive Care, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Japan.
Yudai TakataniDepartment of Primary Care and Emergency Medicine, Kyoto University Hospital, Kyoto, Japan.
Akihito TampoDepartment of Emergency Medicine, Asahikawa Medical University, Asahikawa, Japan.
Yoshihiko NakamuraDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Katsunori MochizukiEmergency Department and Intensive Care Unit, Azumino Red Cross Hospital, Azumino, Japan.
Noritaka YadaDepartment of General Medicine, Nara Medical University, Nara, Japan.
Kaoru KawasakiDepartment of Obstetrics and Gynecology, Kinki University, Faculty of Medicine, Osakasayama, Japan.
Akira KiyokawaDepartment of Obstetrics and Gynecology, Kurashiki Central Hospital, Kurashiki, Japan.
Mamoru MorikawaDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Japan.
Mitsuhiro UchibaDepartment of Blood Transfusion and Cell Therapy, Kumamoto University Hospital, Kumamoto, Japan.
Takeshi MatsumotoDepartment of Transfusion Medicine and Cell Therapy, Mie University Hospital, Mie, Japan.
Hidesaku AsakuraDepartment of Hematology, Kanazawa University Hospital, Kanazawa, Japan.
Seiji MadoiwaDepartment of Clinical Laboratory Medicine, Tokyo Saiseikai Central Hospital, Tokyo, Japan.
Toshimasa UchiyamaDepartment of Laboratory Medicine, NHO Takasaki General Medical Center, Takasaki, Japan.
Shinya YamadaDepartment of Hematology, Kanazawa University Hospital, Kanazawa, Japan.
Shin KogaDepartment of Internal Medicine, SBS Shizuoka Health Promotion Center, Shizuoka, Japan.
Takashi ItoDepartment of Hematology and Immunology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Toshiaki IbaDepartment of Emergency and Disaster Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Noriaki KawanoDepartment of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Satoshi GandoDepartment of Acute and Critical Care Medicine, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan.
Hideo WadaAssociated Department With Mie Graduate School of Medicine, Mie Prefectural General Medical Center, Mie, Japan.
Committee of the Clinical Practice Guidelines for Disseminated Intravascular Coagulation 2024, the Japanese Society on Thrombosis, Hemostasis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated intravascular coagulation (DIC) is a complex condition with diverse etiologies. While its association with sepsis has been widely studied, less focus has been given to DIC arising from other critical conditions, such as trauma, burns, acute pancreatitis, and obstetric complications. The 2024 Clinical Practice Guidelines, developed by the Japanese Society on Thrombosis and Hemostasis (JSTH), aim to fill this gap and offer comprehensive recommendations for managing DIC across various conditions. This study, Part 4 of the guideline series, addresses DIC management in trauma, burns, obstetric complications, acute pancreatitis/liver failure, viral infections, and autoimmune diseases. For trauma-associated DIC, early administration of fresh-frozen plasma (FFP), coagulation factor concentrates such as fibrinogen and prothrombin complex concentrates, and tranexamic acid is recommended. The guidelines also highlight DIC in obstetrics, which is associated with massive bleeding, and recommend the administration of fibrinogen concentrate, antithrombin concentrate, and tranexamic acid. Through a systematic review of the current evidence, the guidelines provide stratified recommendations aimed at improving clinical outcomes in DIC management beyond sepsis, thereby serving as a valuable resource for healthcare providers globally.

Indexed as

Disseminated Intravascular CoagulationPancreatitisWounds and InjuriesAcute DiseaseDisease ManagementFemaleHumansJapanLiver FailurePregnancyTranexamic AcidTranexamic AcidDisseminated intravascular coagulationLiver failureObstetricsPancreatitisTrauma

Identifiers

PMID39890756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.