ArticleArchives of dermatological research2025
Typha pollen extract inhibit melanogenesis via α-MSH/MC1R signaling pathway in B16 and melasma mouse model.
Article in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Heat Stress Modulates WDR5-Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- CXCL1-CXCR2 axis inhibits melanogenesis through the suppression of the WNT/β-catenin pathway.Frontiers in immunology · 2026Article
- Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology.Journal of cosmetic dermatology · 2026Review
- Liquid Chromatography Quadrupole Time-of-Flight Tandem Mass Spectrometry Characterization of Ethyl Acetate Fraction fromInternational journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate the effects of Typha Pollen extract on melanogenesis in B16 and melasma mouse model. The effects of TP extract on B16 viability, melanin content of B16, MC1R content and TYR activity were studied by MTT assay, NaOH method, ELISA assay and dopa oxidation assay, respectively. In melasma mouse model, the effects of TP extract on MC1R content, MITF content and TYR activity were studied by ELISA assay, immunofluorescence staining and dopa oxidation assay, respectively. The results showed that the appropriate concentration of TP extract does not affect cell viability, and that TP extract inhibit B16 melanin, MC1R content and TYR activity. The results showed that TP extract inhibit skin MC1R content, MITF content and TYR activity. TP extract inhibit B16 melanin, inhibit proteins of α-MSH/MC1R signaling pathway such as MC1R, MITF and TYR. So TP extract is a natural and effective potential whitening agent.
Indexed as
Identifiers
39890718What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.