Evidence map›Paper›PMID 39890669›Full record

ArticleActa neurochirurgica2025

Perioperative complications in spinal trauma patients: does timing matter?

Charlotte Y Adegeest, Cas J Hilke, Godard C W de Ruiter, Mark P Arts, Carmen L Vleggeert-Lankamp, Raoul D Martin, Wilco C Peul, Paula Valerie Ter Wengel

Abstract read
In one paragraph

Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Early surgical stabilization reduces perioperative complications in older adults with thoracolumbar fractures from high-energy trauma: a propensity score-matched analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
  4. Article
  5. Association Betweenn Preoperative RDW and Postoperative Pulmonary Embolism in Trauma Patients: A Propensity Score-Matched Multicenter Cohort Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Charlotte Y AdegeestDepartment of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands. c.y.adegeest@lumc.nl.ORCID 0000-0003-1865-9252
Cas J HilkeDepartment of Neurology, Spaarne Gasthuis, Haarlem, The Netherlands.
Godard C W de RuiterDepartment of Neurosurgery, Haaglanden Medical Center, The Hague, The Netherlands.
Mark P ArtsDepartment of Neurosurgery, Haaglanden Medical Center, The Hague, The Netherlands.
Carmen L Vleggeert-LankampDepartment of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
Raoul D MartinDepartment of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
Wilco C PeulDepartment of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
Paula Valerie Ter WengelDepartment of Neurosurgery, Haaglanden Medical Center, The Hague, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly surgery in traumatic spinal fracture treatment may facilitate prompt mobilization, encountering affiliated complications. However, the safety and the benefits of early surgery are being questioned in spinal trauma patients. Therefore, the objective of this retrospective study is to investigate the effect of surgical timing on perioperative complications in these patients.

methodsSpinal trauma patients who underwent surgery between 2010 and 2020 in two Dutch Level-I trauma centers were included retrospectively and divided into an early (< 24 h), late (between 24 and 72 h) and delayed (> 72 h) surgical cohort. The primary outcome was the occurrence of peri-operative complications. Besides surgical timing, trauma and patient-specific factors were also analyzed as potential risk factors for the occurrence of complications.

resultsA total of 394 patients were included, of whom 149 received early, 159 late and 86 delayed surgical treatment. The occurrence of perioperative complications was significantly associated with age, body mass index, comorbidities, ASA grade 3 and 4, spinal cord injury (SCI), AO Spine type C injury, additional chest injury, and surgical delay. A multivariable analysis showed that age, ASA category, AO Spine classification and SCI were significantly associated with perioperative complications. Moreover, a subsequent analysis in non-SCI patients demonstrated an association between perioperative complications and delayed surgery.

conclusionsIn this study, delayed surgical treatment is potentially associated with more perioperative complications compared to early surgery in non-SCI patients. Other possible risk factors for the occurrence of perioperative complications may be older age, ASA 3 and 4, AO spine C injury and SCI.

Indexed as

Postoperative ComplicationsSpinal Cord InjuriesSpinal FracturesSpinal InjuriesTime-to-TreatmentAdultAgedFemaleHumansMaleMiddle AgedNetherlandsRetrospective StudiesRisk FactorsTime FactorsYoung AdultRisk factorsSpinal cord InjurySpinal traumaSurgical timingTreatment

Identifiers

PMID39890669
PMCPMC11785685

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.