ArticleThe Lancet. Global health2025
Variability and social patterning of cancer mortality in 343 Latin American cities: an ecological study.
Article in The Lancet. Global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed.
- Demographic trends and geographic disparities in malignant neoplasm of eye and adnexa-related mortality in the United States, 1999-2023.Eye (London, England) · 2026Article
- Patterns of sex differences in cancer mortality in Colombia: a population-based analysis, 1980-2023.Lancet regional health. Americas · 2026Article
- Radiotherapy access in Latin America: Socio-economic determinants and equity challenges socio-economic determinants in Latin America for radiotherapy.Clinical and translational radiation oncology · 2026Article
- The global cancer crisis: a review of growing burden, deepening inequality and initiatives for prevention and early detection.Ecancermedicalscience · 2026Review
- Cancer Incidence and Mortality Estimates in Latin America and the Caribbean: A Systematic Analysis of the GLOBOCAN 2022.Cancer research communications · 2025Article
- Global epidemiological trends in prostate cancer burden: a comprehensive analysis from Global Burden of Disease Study 2021.Translational andrology and urology · 2025Article
- Global burden of disease for colorectal cancer due to diet low in whole grains from 1990 to 2021 and its projections to 2050: analysis of the global burden of disease study 2021.Frontiers in nutrition · 2025Article
- Co-occurrence patterns of esophageal and stomach cancer across 204 countries and territories: a spatial correspondence and systematic analysis.Frontiers in oncology · 2025Article
- Essential medicines in Central America: Analysis of national lists, macroeconomic factors, and alignment with health priorities.The journal of medicine accessArticle
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Abstract
backgroundUnderstanding between-city variations in cancer mortality is crucial to inform national and subnational cancer prevention strategies. However, studies at the city level in Latin America are scarce. As part of the Salud Urbana en América Latina (SALURBAL) project, we aimed to describe the variability in cancer mortality rates across 343 cities in nine Latin American countries and the associations of these rates with city-level socioeconomic development.
methodsThis ecological study used data from cities in Argentina, Brazil, Chile, Colombia, Costa Rica, El Salvador, Guatemala, Mexico, and Panama. Vital registration and population data from Jan 1, 2015 to Dec 31, 2019 were used to estimate sex-specific and age-standardised cancer mortality rates for each city, overall and for seven cancer sites (breast, lung, colorectal, stomach, liver, prostate, and cervical), and the associations of these rates with city-level socioeconomic development.
findingsWe found wide variability in cancer mortality by city (overall age-adjusted cancer mortality rates varied by almost three times), sex, and cancer site. Variability between cities within the same country was highest for cervical and prostate cancer. The most common causes of cancer deaths were breast cancer (305 cities) for females and prostate cancer (167 cities) and lung cancer (132 cities) for males. Liver and cervical cancer were the primary cause of cancer mortality in fewer than ten cities each, most of which were in Guatemala and Mexico. Lower city-level socioeconomic development was associated with higher mortality from liver, stomach, cervical, and prostate cancers and lower mortality from breast, colorectal, and lung cancers, with variations by sex.
interpretationWe found considerable heterogeneity in cancer mortality between cities, geographical patterning, and associations between cancer mortality rates and socioeconomic development. Our results highlight the need to consider city contexts when planning interventions to reduce cancer mortality and when guiding future cancer prevention and control efforts in urban areas within the region.
fundingWellcome Trust. TRANSLATIONS: For the Spanish and Portuguese translations of the abstract see Supplementary Materials section.
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