Evidence map›Paper›PMID 39890133›Full record

ArticleBMJ open2025

Evaluation of the protective efficacy of OlysetPlus ceiling nets for reduction of malaria incidence in children in Homa Bay County, Kenya: a cluster-randomised controlled study protocol.

Yura K Ko, Wataru Kagaya, Protus Omondi, Kelvin B Musyoka, Takatsugu Okai, Chim W Chan, James Kongere, Victor Opiyo, Jared Oginga, Samuel Mungai and 10 more

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yura K Ko1Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institute, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-3493-0180
Wataru KagayaNagasaki University, Nagasaki, Nagasaki, Japan wataru.kagaya@nagasaki-u.ac.jp.ORCID http://orcid.org/0000-0003-0998-5267
Protus OmondiOsaka Metropolitan University, Osaka, Osaka, Japan.ORCID http://orcid.org/0009-0006-6351-6428
Kelvin B MusyokaOsaka Metropolitan University, Osaka, Osaka, Japan.
Takatsugu OkaiOsaka Metropolitan University, Osaka, Osaka, Japan.
Chim W ChanOsaka Metropolitan University, Osaka, Osaka, Japan.
James KongereOsaka Metropolitan University, Osaka, Osaka, Japan.
Victor OpiyoCenter for Research in Tropical Medicine and Community Development, Nairobi, Kenya.
Jared OgingaCenter for Research in Tropical Medicine and Community Development, Nairobi, Kenya.
Samuel MungaiMount Kenya University, Thika, Kenya.
Bernard N KanoiMount Kenya University, Thika, Kenya.ORCID http://orcid.org/0000-0003-2772-7579
Mariko KanamoriStockholm University, Stockholm, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-8733-1336
Daisuke YoneokaNational Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan.
Kenya National Bureau of Statistics (KNBS)
Kibor K KeitanyKenya National Malaria Control Program, Nairobi, Nairobi, Kenya.
Elijah SongokKenya Medical Research Institute, Nairobi, Kenya.
Gordon Odhiambo OkomoMinistry of Health, Homa Bay, Kenya.
Noboru MinakawaNagasaki University, Nagasaki, Nagasaki, Japan.
Jesse GitakaResearch and Innovation, Mount Kenya University, Thika, Kenya.
Akira Kaneko1Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institute, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMalaria is still a major health problem in sub-Saharan Africa, where 98% of global malaria mortality occurs. In addition, the spread of

methodsA cluster-randomised controlled trial is designed to evaluate the impact of pyrethroid-PBO ceiling nets in Ndhiwa Sub-County, Homa Bay County, Kenya. A total of 44 clusters will be randomly assigned in a 1:1 ratio to the intervention group (pyrethroid-PBO ceiling nets) and the control group. The assignment will be accomplished through covariate-constrained randomisation of clusters. For the primary outcome of clinical malaria incidence, 38 children from each cluster will be enrolled in a cohort and followed for 18 months. We will also evaluate the effects of the intervention on entomological indicators as well as its acceptance by communities and cost-effectiveness. ETHICS AND DISSEMINATION: Ethics approvals were provided by the Mount Kenya University Institutional Scientific Ethics Review Committee and the Ethics Committee Osaka Metropolitan University. Study results will be shared with study participants and communities, the Homa Bay County government and the Kenya National Malaria Control Programme. Results will also be disseminated through publications, conferences and workshops to help the development of novel malaria control strategies in other malaria-endemic countries. TRIAL REGISTRATION NUMBER: UMIN000053873.

Indexed as

Insecticide-Treated BednetsMalaria, FalciparumMosquito ControlAnimalsChildChild, PreschoolFemaleHumansIncidenceInfantKenyaMalePyrethrinsRandomized Controlled Trials as TopicPyrethrinsInfection controlMalariaMosquito Vectors

Identifiers

PMID39890133
PMCPMC11795387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.