Evidence map›Paper›PMID 39889929›Full record

ArticleJournal of affective disorders2025

Disparities in group-based medical mistrust and associations with mental health symptoms during the COVID-19 pandemic.

Jeremy W Luk, LaToya Sewell, Bethany L Stangl, Courtney L Vaughan, Andrew J Waters, Melanie L Schwandt, David Goldman, Vijay A Ramchandani, Nancy Diazgranados

Abstract read
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In one paragraph

Article in Journal of affective disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jeremy W LukOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA. Electronic address: jeremy.luk@nih.gov.
LaToya SewellOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
Bethany L StanglHuman Psychopharmacology Laboratory, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
Courtney L VaughanDepartment of Medical and Clinical Psychology, Uniformed Services University, Bethesda, MD, USA.
Andrew J WatersDepartment of Medical and Clinical Psychology, Uniformed Services University, Bethesda, MD, USA.
Melanie L SchwandtOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
David GoldmanOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA; Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA.
Vijay A RamchandaniHuman Psychopharmacology Laboratory, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
Nancy DiazgranadosOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.

Funding

NIAAA Repository/Screening Database Management and ResearchZIAAA000130 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI SCHWANDT, MELANIE · 2017 to 2025
$60.1M
Alcohol Pharmacokinetics and Pharmacodynamics in HumansZIAAA000466 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI RAMCHANDANI, VIJAY ARJUN · 2009 to 2025
$31.2M
Alcohol Pharmacokinetics and Pharmacodynamics in HumansZ01AA000466 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI RAMCHANDANI, VIJAY ARJUN · 2006 to 2008
$762k
Intramural NIH HHS Z01 AA000466Intramural NIH HHS ZIA AA000130Intramural NIH HHS ZIA AA000466
6 · The paper itself

Abstract

backgroundRacial/ethnic disparities in health-related outcomes may have been exacerbated during the COVID-19 pandemic. Individuals from racial/ethnic minority groups or with a history of alcohol use disorder (AUD) may have greater medical mistrust. We examined racial/ethnic and AUD-related differences in group-based medical mistrust during the pandemic and tested whether medical mistrust dimensions were associated with mental health symptoms.

methodsTwo hundred and fifty participants from the National Institute on Alcohol Abuse and Alcoholism COVID-19 Pandemic Impact on Alcohol Study completed an online survey between April and July of 2022. Exploratory factor analysis and path analysis were conducted.

resultsGroup-based medical mistrust scores were elevated among participants who identified as Non-Hispanic Black and those with a history of AUD. Two medical mistrust dimensions were found: (1) Suspicion and Lack of Provider Support, and (2) Group Disparities in Health Care. Compared to Non-Hispanic White participants, Non-Hispanic Black participants reported higher scores on the Suspicion and Lack of Provider Support dimension of medical mistrust, which was associated with higher mental health symptoms. This medical mistrust dimension was also a significant mediator of the observed group differences in mental health symptoms. LIMITATIONS: Cross-sectional data, aggregation of racial/ethnic groups with small sample sizes, and nonrepresentative sample.

conclusionsNon-Hispanic Black individuals and individuals with AUD may be more vulnerable to mental health symptoms due to higher suspicion toward medical professionals and healthcare systems and perceived lack of support from healthcare providers. Increased awareness among healthcare providers may help address medical mistrust, encourage help-seeking behaviors, and alleviate mental health symptoms.

Indexed as

AlcoholismCOVID-19Healthcare DisparitiesMental HealthTrustAdultBlack or African AmericanFemaleHumansMaleMiddle AgedUnited StatesWhiteAnxietyDepressionHealth disparitiesMedical mistrustMental health

Identifiers

PMID39889929
PMCPMC11938257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.