Evidence map›Paper›PMID 39889354›Full record

ArticleJournal of neural engineering2025

Intrathecal delivery of BDNF to the lumbar spinal cord modulates lumbar interneurons activity in a feline model of spinal cord injury.

J Paz Amaya, F Marchionne, A J Krupka, T Duong, M A Lemay

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neural engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J Paz AmayaDepartment of Bioengineering, Temple University, 1947 N 12th St, Philadelphia, PA 19122, United States of America.ORCID 0009-0008-4271-4470
F MarchionneDepartment of Bioengineering, Temple University, 1947 N 12th St, Philadelphia, PA 19122, United States of America.
A J KrupkaCollege of Sciences, DeSales University, 2755 Station Ave, Center Valley, PA 18034, United States of America.
T DuongDepartment of Bioengineering, Temple University, 1947 N 12th St, Philadelphia, PA 19122, United States of America.
M A LemayDepartment of Bioengineering, Temple University, 1947 N 12th St, Philadelphia, PA 19122, United States of America.ORCID 0000-0002-5636-0297

Funding

SurgeryP01NS055976 · NINDS · DREXEL UNIVERSITY · PI TOM, VERONICA JEAN · 2007 to 2017
$12.3M
Intrathecal pump delivery of neurotrophins for locomotor recovery after spinal cord injuryR01NS110605 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI LEMAY, MICHEL A · 2020 to 2023
$1.4M
Intrathecal pump delivery of neurotrophins for locomotor recovery after spinal cord injuryR56NS110605 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI LEMAY, MICHEL A · 2019 to 2019
$352k
NINDS NIH HHS P01 NS055976NINDS NIH HHS R01 NS110605NINDS NIH HHS R56 NS110605
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain-Derived Neurotrophic FactorInterneuronsSpinal CordSpinal Cord InjuriesAnimalsCatsDisease Models, AnimalFemaleInjections, SpinalLumbar VertebraeMaleRecovery of FunctionBrain-Derived Neurotrophic FactorBDNFextracellular recordingsfeline modelslocomotor recoveryneurotrophin deliveryspinal cord injuryspinal interneurons

Identifiers

PMID39889354
PMCPMC12198982

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.