Evidence map›Paper›PMID 39888996›Full record

ArticleScience advances2025

VPS18 contributes to phagosome membrane integrity in

Charul Jani, Neha Jain, Amanda K Marsh, Pooja Uchil, Triet Doan, Meggie Hudspith, Owen T Glover, Zach R Baskir, Julie Boucau, David E Root and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Restricted MHC-II trafficking inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Control of antigen presentation on MHC-I by a bacterial secretion system.bioRxiv : the preprint server for biology · 2025
    Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Charul JaniThe Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.ORCID 0009-0002-7521-8031
Neha JainThe Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Amanda K MarshThe Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.ORCID 0009-0009-6074-6369
Pooja UchilThe Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Triet DoanThe Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.ORCID 0009-0007-2235-2567
Meggie HudspithElectron Microscopy Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, The Netherlands.ORCID 0000-0002-6069-8338
Owen T GloverThe Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Zach R BaskirThe Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Julie BoucauThe Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0001-6731-7238
David E RootThe Broad Institute, Cambridge, MA 02139, USA.ORCID 0000-0001-5122-861X
Nicole N van der WelElectron Microscopy Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, The Netherlands.ORCID 0000-0001-6392-3417
John G DoenchThe Broad Institute, Cambridge, MA 02139, USA.ORCID 0000-0002-3707-9889
Amy K BarczakThe Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0003-3806-2381

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
Project 2: Genes required for dendritic cell responses to pathogens and T cellsU19AI133524 · NIAID · HARVARD MEDICAL SCHOOL · PI SHARPE, ARLENE H. · 2017 to 2021
$12.3M
Center for Open Bioimage AnalysisP41GM135019 · NIGMS · BROAD INSTITUTE, INC. · PI CARPENTER, ANNE E., CIMINI, BETH · 2020 to 2024
$6.9M
Elucidating the path to type I IFNs in TB infectionR01AI150762 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI BARCZAK, AMY K · 2021 to 2025
$3.2M
NIAID NIH HHS P30 AI060354NIAID NIH HHS R01 AI150762NIAID NIH HHS U19 AI133524NIGMS NIH HHS P41 GM135019
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MacrophagesMycobacterium tuberculosisPhagosomesTuberculosisVesicular Transport ProteinsAnimalsAutophagyHost-Pathogen InteractionsHumansMiceVesicular Transport Proteins

Identifiers

PMID39888996
PMCPMC11784855

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.