ArticleScience advances2025
Mechanisms of uropathogenic
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Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9citing papers in PubMed
–field-weighted citation impact
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Who cites it
9 citing papers in PubMed.
- IL-17B protects against uropathogenicMicrobiology spectrum · 2026Article
- An update on Escalating Drug Resistance among Uropathogenic Bacteria: Challenges in Treatment and Scope for Maneuver.Current microbiology · 2026Review
- How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection.Immunological reviews · 2026Review
- Cocktail of genetically diverse lytic phages reduces uropathogenic Escherichia coli colonization in mouse urinary tract.Scientific reports · 2026Article
- HMGB1 functions as a critical mediator of host defense at the gut mucosal barrier.Cell host & microbe · 2026Article
- The Yeh pilus adhesin is equipped with an α-helical flap motif, which contributes to pectin adherence.Science advances · 2026Article
- Functional Characterization ofAntibiotics (Basel, Switzerland) · 2026Article
- Genotypic Characterization of Virulence Factors in Extended-Spectrum Beta-Lactamase (ESBL)-ProducingAntibiotics (Basel, Switzerland) · 2025Article
- Uropathogenic Escherichia coli niche occupancy determines the effects of mucosal vaccine against FimH.Cell reports · 2025Article
Corrections and comments
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Authors and funding
17 authors.
Philippe N AzimzadehDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-8172-5051
George M BirchenoughDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-2283-2353
Nathaniel C GualbuertoDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0009-0009-2697-5862
Jerome S PinknerDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-7389-7440
Kevin O TamadonfarDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.
Wandy BeattyDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-0715-7361
Thomas J HannanDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-0498-8231
Karen W DodsonDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.
Enid C IbarraDepartment of Internal Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.
Seonyoung KimDepartment of Internal Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-8854-287X
Henry L SchreiberDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-4501-9886
James W JanetkaCenter for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-9888-5411
Andrew L KauCenter for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-9386-3766
Ashlee M EarlInfectious Disease and Microbiome Program, Broad Institute, Cambridge, MA 02142, USA.ORCID 0000-0001-7857-9145
Mark J MillerDepartment of Internal Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-5676-389X
Gunnar C HanssonDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-1900-1869
Scott J HultgrenDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-8785-564X
Funding
Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI NEAFSEY, DANIEL E · 2014 to 2024
$66.5MTRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGYT32GM007067 · NIGMS · WASHINGTON UNIVERSITY · PI TRUE-KROB, HEATHER L · 1985 to 2020
$20.4MMucosal Immune Defense Mechanisms of the Urinary BladderU01AI095542 · NIAID · WASHINGTON UNIVERSITY · PI COLONNA, MARCO, HULTGREN, SCOTT J. · 2011 to 2020
$9.8MTraining Program in Cellular and Molecular BiologyT32GM139774 · NIGMS · WASHINGTON UNIVERSITY · PI HEATHER L TRUE-KROB · 2021 to 2026
$6.7MEpidemiologic and molecular basis of the gut-urinary tract axis in urinary tract infectionR01DK121822 · NIDDK · WASHINGTON UNIVERSITY · PI Ashlee Miriam Earl, SCOTT J. HULTGREN · 2020 to 2026
$4.9MHarnessing Antibody Responses to Prevent and Treat Urinary Tract InfectionsR01AI165915 · NIAID · WASHINGTON UNIVERSITY · PI Andrew Leon Kau · 2022 to 2026
$3.1MPathogenic Fiber Formation in Bacteria: Structural BasisR37AI048689 · NIAID · WASHINGTON UNIVERSITY · PI SCOTT J. HULTGREN · 2021 to 2026
$2.9MThe MUC2 Mucus Gel as an Innate Immune Mechanism that Inhibits InflammationU01AI095473 · NIAID · GOTEBORG UNIVERSITY · PI HANSSON, GUNNAR C., JOHANSSON, MALIN E.V. · 2011 to 2020
$2.6MMucosal Immune Defense Mechanisms of the Urinary BladderR01DK132327 · NIDDK · WASHINGTON UNIVERSITY · PI MARCO COLONNA, SCOTT J. HULTGREN · 2023 to 2026
$2.5MNIAID NIH HHS R01 AI165915NIAID NIH HHS R37 AI048689NIAID NIH HHS U01 AI095473NIAID NIH HHS U01 AI095542NIAID NIH HHS U19 AI110818NIDDK NIH HHS R01 DK121822NIDDK NIH HHS R01 DK132327NIGMS NIH HHS T32 GM007067NIGMS NIH HHS T32 GM139774
Abstract
Urinary tract infections (UTIs) are highly recurrent and frequently caused by Uropathogenic
Indexed as
Escherichia coli InfectionsGastrointestinal TractIntestinal MucosaUrinary Tract InfectionsUropathogenic Escherichia coliAdhesins, Escherichia coliAnimalsBacterial AdhesionFimbriae ProteinsHumansMiceAdhesins, Escherichia coliFimbriae ProteinsfimH protein, E coli
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.